| Sequence 1: | NP_001285314.1 | Gene: | vap / 32569 | FlyBaseID: | FBgn0003969 | Length: | 954 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001381939.1 | Gene: | DAB2IP / 153090 | HGNCID: | 17294 | Length: | 1189 | Species: | Homo sapiens |
| Alignment Length: | 517 | Identity: | 140/517 - (27%) |
|---|---|---|---|
| Similarity: | 238/517 - (46%) | Gaps: | 69/517 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 428 IDLSC---AYLYQCHDSLWERPYCFQIVERALPCLATVTYLCAPSQESYVEWINSLKAQCDSQLS 489
Fly 490 RAQKKVSRLRELRCLNLHVLEAHRLPFKLVPHPY-CSISLNQVKVGKTRVKIAPEPV-WEEEFVL 552
Fly 553 DDVPPDVVSLTITLI----SRGKRGKDSEVAELTIDLSSLKNGQETEGWYQLTGMTPMGEWG--- 610
Fly 611 SLRLRMRYLDDLIMPCEEYSPLQQLLLESELYAVKALAE-LCHNDRVPLATALLRVFRQEKRETE 674
Fly 675 LIRMLCQAEVTR--ENETTTLFRGASLATTLMDLYMRTECSGFLQSAVSETVQRILESKQSAELN 737
Fly 738 PTKMDVNDDACTNAEF------LLQILDLVTQSIFTSPDACPRNVRFICSCLQKAVMAKWPTERL 796
Fly 797 VR------TRVVSGFIFLRLLCPALLNPRQFGLVSETPPMAATRSLVMVAKCLQNLANLIEFGGK 855
Fly 856 EQYMEVVNPFILKNKERMIVFLDQLSSVNDPNQPLGM--FVEQSTNLNSQDTGRELATLHHI 915 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| vap | NP_001285314.1 | SH2_Nterm_RasGAP | 64..166 | CDD:198216 | |
| SH3_RasGAP | 183..241 | CDD:212722 | |||
| SH2_Cterm_RasGAP | 252..326 | CDD:198217 | |||
| PH_RASA1 | 379..484 | CDD:270080 | 12/58 (21%) | ||
| C2_Ras_p21A1 | 499..622 | CDD:176045 | 36/131 (27%) | ||
| RasGAP | 620..954 | CDD:413381 | 89/313 (28%) | ||
| DAB2IP | NP_001381939.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..75 | ||
| Necessary for interaction with AKT1. /evidence=ECO:0000269|PubMed:19903888 | 646..943 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 653..678 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 715..742 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 803..823 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 843..865 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 895..998 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1015..1035 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1164..1189 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3508 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D44624at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||