DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8939 and CG5220

DIOPT Version :9

Sequence 1:	NP_573099.1	Gene:	CG8939 / 32568	FlyBaseID:	FBgn0030720	Length:	817	Species:	Drosophila melanogaster
Sequence 2:	NP_650590.1	Gene:	CG5220 / 42056	FlyBaseID:	FBgn0038471	Length:	302	Species:	Drosophila melanogaster

Alignment Length:	246	Identity:	85/246 - (34%)
Similarity:	132/246 - (53%)	Gaps:	19/246 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VGKTRKDK---FYQLAKETGLRSRAAFKLIQLNRKFGFLQQSQVCLDLCAAPGGWMQVAKQNM-- 66
            :|||.|||   :|:.||:.|.|:|:||||:.::..:|.|...|..:|||||||.|.||..:.:
  Fly     1 MGKTSKDKRDIYYRQAKDEGWRARSAFKLLHVDEAYGILNGVQRAVDLCAAPGSWSQVLSRKLYD 65

  Fly    67 ------PVSSI-VIGVDLFPIRPIAGCIGLVEDITTEKCRQSLTKEL-QSWKADVVLHDGAPNVG 123
                  ..|:: :|.|||..:.||.|.:.|..|||.:...:::.... .:.||.:|:.||||:|.
  Fly    66 TCETDDEKSAVKIIAVDLQAMAPIRGILQLQGDITKQSTAEAIIGHFGGNEKAQLVVCDGAPDVT 130

  Fly   124 RNWLYDAYQQICLTLNALKLSTQFLRNGGWFVTKVFRSKDYNALLWVLKQLFKKVHATKPSASRK 188
            .....|.|.|..|.:.||.::|..|..||.||.|:|:....:.|...::..|||....||.:||.
  Fly   131 GVHEMDEYMQHQLLVAALSIATCVLETGGTFVAKIFKGNATSLLSSQMQIFFKKFDIYKPPSSRP 195

  Fly   189 ESAEIFVVCQGYLAPDHIDPRLLDSKYVFEELDLDAKKKSSLLHPEKQKRI 239
            .|.|.||||..:..|:...|::::.  ..:::.|.|:|..|    |..:|:
  Fly   196 SSIEAFVVCSDFCLPEGYIPQVINP--ARDDIRLLAQKTGS----EVNRRL 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8939	NP_573099.1	RlmE	8..203	CDD:223370	77/207 (37%)
		DUF3381	233..366	CDD:288694	2/7 (29%)
		Spb1_C	611..803	CDD:285075
CG5220	NP_650590.1	RlmE	3..211	CDD:223370	76/207 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440466
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0293
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1362679at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10920
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850