DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8939 and FTSJ1

DIOPT Version :9

Sequence 1:	NP_573099.1	Gene:	CG8939 / 32568	FlyBaseID:	FBgn0030720	Length:	817	Species:	Drosophila melanogaster
Sequence 2:	NP_036412.1	Gene:	FTSJ1 / 24140	HGNCID:	13254	Length:	329	Species:	Homo sapiens

Alignment Length:	372	Identity:	119/372 - (31%)
Similarity:	169/372 - (45%)	Gaps:	70/372 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VGKTRKDK---FYQLAKETGLRSRAAFKLIQLNRKFGFLQQSQVCLDLCAAPGGWMQVAKQNM-- 66
            :|:|.|||   :|:||||.|.|:|:||||:||:::|...|.....:|||||||.|.||..|.:
Human     1 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLSQKIGG 65

  Fly    67 PVSSIVIGVDLFPIRPIAGCIGLVEDITTEKCRQSLTKELQSWKADVVLHDGAPNVGRNWLYDAY 131
            ..|..|:.|||..:.|:.|.:.:..|||.....:.:.:..:...||:|:.||||:|......|.|
Human    66 QGSGHVVAVDLQAMAPLPGVVQIQGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGLHDVDEY 130

  Fly   132 QQICLTLNALKLSTQFLRNGGWFVTKVFRSKDYNALLWVLKQLFKKVHATKPSASRKESAEIFVV 196
            .|..|.|.||.::|..|:.||.||.|:||.:|...|...|:..|..|...||.:||..|.|.|.|
Human   131 MQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRNSSIEAFAV 195

  Fly   197 CQGYLAPDHIDP----RLLDSKY--VFEELDLDAKKKSSLLHPEKQKRIKAEGYTAQDIALRNDL 255
            ||||..|:...|    .|||..|  .|.:||             ...||.....|..|
Human   196 CQGYDPPEGFIPDLSKPLLDHSYDPDFNQLD-------------GPTRIIVPFVTCGD------- 240

  Fly   256 AATEFLKAENALAALQGIGSIRIDDQRIANHKKT-------TPEILECCKDLKVLGRKDIKGLVQ 313
                       |::.....|..:|.:..:.:|.|       :|...|.|    .|.||.     |
Human   241 -----------LSSYDSDRSYPLDLEGGSEYKYTPPTQPPISPPYQEAC----TLKRKG-----Q 285

  Fly   314 WWKDVRELFVEKETPLVVGNAADEKPKPLTQAEIE-----DMEDAEL 355
            ..|::|    .::.|:   :..|..|:||...:..     :|||.|:
Human   286 LAKEIR----PQDCPI---SRVDTFPQPLAAPQCHTLLAPEMEDNEM 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8939	NP_573099.1	RlmE	8..203	CDD:223370	83/199 (42%)
		DUF3381	233..366	CDD:288694	27/135 (20%)
		Spb1_C	611..803	CDD:285075
FTSJ1	NP_036412.1	RlmE	4..203	CDD:223370	82/198 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0293
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1362679at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820