DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8939 and R74.7

DIOPT Version :9

Sequence 1:	NP_573099.1	Gene:	CG8939 / 32568	FlyBaseID:	FBgn0030720	Length:	817	Species:	Drosophila melanogaster
Sequence 2:	NP_497843.1	Gene:	R74.7 / 175543	WormBaseID:	WBGene00011281	Length:	337	Species:	Caenorhabditis elegans

Alignment Length:	387	Identity:	113/387 - (29%)
Similarity:	180/387 - (46%)	Gaps:	84/387 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VGKTRKDK---FYQLAKETGLRSRAAFKLIQLNRKFGFLQQSQVCLDLCAAPGGWMQVAKQNM-- 66
            :|||.:||   :|:||||...|:|:||||:|::.:|..|:..:..:|||||||.|.||..:.:
Worm     1 MGKTSRDKRDIYYRLAKENKWRARSAFKLMQIDDEFQILKGVRRAVDLCAAPGSWSQVLSKRLYE 65

  Fly    67 -PVSSIVIGVDLFPIRPIAGCIGLVEDITTEKCRQSLTKELQSWKADVVLHDGAPNVGRNWLYDA 130
             ...:.::.:||.|:.||.|.|.|..|||:......:.|.....|:|:|:.||||:|......|.
Worm    66 EDQEAKIVAIDLQPMAPIPGVIQLQGDITSVDTANQVIKHFSGEKSDIVICDGAPDVTGIHSLDE 130

  Fly   131 YQQICLTLNALKLSTQFLRNGGWFVTKVFRSKDYNALLWVLKQLFKKVHATKPSASRKESAEIFV 195
            :.|..|.|.|..:::..|:.||.|:.|:|||::.:.|...:|:.||||:..||.:||:.|.|.||
Worm   131 FMQAELILAAFNITSHVLKEGGNFLAKIFRSRNSSLLYAQMKKYFKKVYLAKPRSSRQSSCEAFV 195

  Fly   196 VCQGYLAPD-----------------HIDPRLLD--------SKYVFEE---LDLDAKKKSSLLH 232
            :|..|..|:                 .|.|.::|        |.:..|:   ||:||......:.
Worm   196 LCLDYSPPEGFVPTMGKTSLDATDASAISPDIIDGFVTCGDLSGWDSEKSYPLDIDACFPKGEID 260

  Fly   233 PEKQKRIKAEGYTAQDIALRNDLAATEFLKAENALAALQGIGSIRIDDQRIANHKKTTPEILECC 297
            .|::||     |..:|:.......|.:        |||.               ||.:....:..
Worm   261 EEQKKR-----YEFKDVVQPPTDPAYK--------AALD---------------KKKSGVFAKMS 297

  Fly   298 KDLKVLGRKDIKGLVQWWKDVRELFVEKETPLVVGNAADEKPKPLTQAEIEDMEDAELQTQI 359
            .||    .:.:|..:...||      :|:||      |:..|      .:|::|.|..:.|:
Worm   298 ADL----NRQLKAELSRGKD------QKKTP------AENVP------SVEELEKAAEKFQL 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8939	NP_573099.1	RlmE	8..203	CDD:223370	78/200 (39%)
		DUF3381	233..366	CDD:288694	25/127 (20%)
		Spb1_C	611..803	CDD:285075
R74.7	NP_497843.1	RlmE	3..204	CDD:223370	77/200 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0293
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1362679at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820