Protein Alignment CG8939 and H06I04.3

DIOPT Version :10

• Sequence 1: NP_573099.1
• Gene: CG8939 / 32568
• FlyBaseID: FBgn0030720
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_497655.1
• Gene: H06I04.3 / 175414
• WormBaseID: WBGene00019168
• Length: 833
• Species: Caenorhabditis elegans
• Alignment Length: 874
• Identity: 356/874 - (40%)
• Similarity: 506/874 - (57%)
• Gaps: 118/874 - (13%)

  Fly     1 MGKKTKVGKTRKDKFYQLAKETGLRSRAAFKLIQLNRKFGFLQQSQVCLDLCAAPGGWMQVAKQN 65
            ||||.|:||.|:||:|:||||.|.||||||||:|||::|.||::|:..:|||||||||||||.|.
 Worm     1 MGKKVKIGKQRRDKYYKLAKEAGYRSRAAFKLVQLNKRFEFLEKSRATVDLCAAPGGWMQVASQF 65

  Fly    66 MPVSSIVIGVDLFPIRPIAGCIGLVEDITTEKCRQSLTKELQSWKADVVLHDGAPNVGRNWLYDA 130
            |||||:::||||.||:||..||.|..||||.:.|.::.|||::|.||.||||||||||.||::||
 Worm    66 MPVSSLIVGVDLAPIKPIKNCIALQGDITTNETRAAIKKELKTWSADCVLHDGAPNVGLNWVHDA 130

  Fly   131 YQQICLTLNALKLSTQFLRNGGWFVTKVFRSKDYNALLWVLKQLFKKVHATKPSASRKESAEIFV 195
            :||.||||:||||:||.||.||.||||||||.||:.|:.|.::|||:||..||:|||.|||||||
 Worm   131 FQQNCLTLSALKLATQILRKGGTFVTKVFRSNDYSCLIRVFEKLFKRVHVWKPAASRLESAEIFV 195

  Fly   196 VCQGYLAPDHIDPRLLDSKYVFEELDLDAKKKSSLLHPE-----KQKRIKAEGYTAQDIALRNDL 255
            ||:.|..||.:....||.|.||...|.....|.   :|:     |||:.|||||....:|:.:.:
 Worm   196 VCEVYQKPDKVGAEYLDPKKVFANPDGSEGTKP---NPQNLLIGKQKKAKAEGYDTDSLAIHSTI 257

  Fly   256 AATEFLKAENALAALQGIGSIRIDDQRIANHKKTTPEILECCKDLKVLGRKDIKGLVQWWKDVRE 320
            .||:|:|:...|..|.....|.:||::..||:|||.|::|...|:||||.::::.|::|.|.:.|
 Worm   258 NATDFIKSSGYLDILGTANVITLDDEKWKNHEKTTEEVIEYMNDVKVLGPRELRVLLRWRKSMLE 322

  Fly   321 LFVEKETPLVVGNAAD-EKPKPLTQAEIEDMEDAELQTQIETIVEEEKKDLKRKRKKTLKTKAKL 384
            . :|::...|.|.|.: |..:.||:.::||...||:...|....|:||..||:|:||.||.||::
 Worm   323 T-LEEQRKAVEGEAKEVEIEENLTEEQLEDRAMAEIDELIAKASEDEKAALKKKKKKMLKAKARV 386

  Fly   385 HEKMNLNMVIKGDDGPVEEMEHEIFDLKNIRTSAELDELL-DVQ-PDFAVDESQPEETKLPKYKY 447
            .::..|.|:|.||:||..| :.|:|.||.||.:.||.|:. |.| |||
 Worm   387 LKRRELKMIIDGDEGPQAE-DQEVFQLKKIRKAKELAEITKDTQAPDF----------------- 433

  Fly   448 FDKDEGNINDDLNYDDDNDEEQSEASDDEDQINDKQGLGLSDDDNDEGNAKGKNKRKKRSENPLI 512
                      |:..|.|:|||:                ||.:.:.:....:|:|  ....||.||
 Worm   434 ----------DMMEDGDSDEEE----------------GLGEGEWETHGEEGEN--SDEDENELI 470

  Fly   513 ---KSNDFRDKNTKREQRVQLWYEKDVLQNIQSDDDEETYDLNNLAKEF------KAKGVAVLGE 568
               ||.  ..|..||..|.:.|:||:.:..:.||:|::. ::|.:.|..      |.:..    |
 Worm   471 HTEKSG--MSKMEKRNARTESWFEKEEISGLVSDEDDDD-EMNAIEKHIGKNRSKKTENY----E 528

  Fly   569 STLTPDANEEVVQGKKAKRRARHE-TATKDSSSESSESE-------------------------D 607
            :|::.|.::...:|||..:....: ..|.|:..::||||                         |
 Worm   529 NTVSFDDSKGKKKGKKGGKGGEDDGFNTNDADEQASESESSDAEMDEVAKEKLSRFDAQIDLDDD 593

  Fly   608 DANE--DSDGEQPA--------AGTN----AKKVRLSENEMALGALLTRSKKTRRDLIDAAWNRY 658
            |..|  :.:|.:.|        .|.:    |||.:|:..::|:|..:..|.|..|:|.|.|||||
 Worm   594 DEEERYEDEGRRAAKRKCDKKIIGEDLKPVAKKRKLTPEQLAIGEQMIYSAKAARNLEDEAWNRY 658

  Fly   659 AFNDENVPVWFKLDEDEHMTKPTPVPKELTAEYQRKLQEVNVRPIKKVMEAKARKHRRATKRLAK 723
            |.|||::|.||..||.:|..|.|||.||..|.|:.:::|.|.||.|||.||||||.::..::|..
 Worm   659 ANNDEDLPDWFADDEKKHYFKQTPVTKEQVALYRERMREFNARPSKKVAEAKARKQKKMQRKLES 723

  Fly   724 AKKMAEKIMENSDATNHEKSKQLKKVYKKAQEKKKEVTYVVAKKQTAARRARRPAGVKGRYKVVD 788
            |||.||.|:||....:.||.:::||||..|..|:|:...:|...:....:..||   .|:||:||
 Worm   724 AKKKAEGILENDQMEHSEKVREMKKVYANATRKEKKKVELVRMTKGKKGKTGRP---NGQYKLVD 785

  Fly   789 PREKKDKRSMDAKKRREKGSKGRKGKGRK 817
            .|.|||.|:..||: :.||..|::|..:|
 Worm   786 SRMKKDLRAAKAKE-KTKGRGGKRGIPKK 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8939	NP_573099.1	RlmE	1..200	CDD:440062	133/198 (67%)
		DUF3381	233..366	CDD:463375	48/138 (35%)
		Spb1_C	610..803	CDD:462264	84/206 (41%)
H06I04.3	NP_497655.1	RlmE	9..197	CDD:440062	125/187 (67%)
		DUF3381	237..363	CDD:463375	46/126 (37%)
		PTZ00121	<283..814	CDD:173412	194/589 (33%)
		Spb1_C	618..800	CDD:462264	80/185 (43%)