Protein Alignment exd and PBX4

DIOPT Version :9

• Sequence 1: NP_001259592.1
• Gene: exd / 32567
• FlyBaseID: FBgn0000611
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: XP_011526622.1
• Gene: PBX4 / 80714
• HGNCID: 13403
• Length: 391
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 228/373 - (61%)
• Similarity: 262/373 - (70%)
• Gaps: 48/373 - (12%)

  Fly    39 KQKDIGEILQQIMSISEQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKT--------------- 88
            ::.|..::|||||:|::|||||||||||.|||||||||||||||||||||
Human    15 RRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEIKEKTASSFLTRPCEETTKQ 79

  Fly    89 --VLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIE 151
              ::|||..|:|:|||.||:||||||:||||..|||.|.|.|.|.|..|:.||..:    ||:||
Human    80 AFLVSIRGIQDEDPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCPN----DNSIE 140

  Fly   152 HSDYRAKLAQIRQIYHQELEKYEQACNEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSI 216
            ||||||||:|||||||.|||||||||.||||||.|||:||||.||::||||||||..||.|||:|
Human   141 HSDYRAKLSQIRQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGAIHGKFSAI 205

  Fly   217 QMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGIT 281
            |||||||||||||.||||.||||||||||||||:|:|||||||||:|||||||||||||||.|:|
Human   206 QMQLKQSTCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLT 270

  Fly   282 VSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKAAGASPYSMAG--------PPSGTTTPMMSPA 338
            :|||||||||||||||||:||.||||.:|..|.|...:...:.|        |.||::.|...|:
Human   271 ISQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHASCLSTPSSGSSGPFPLPS 335

  Fly   339 PPQ--------DSMGYPMGSGGYDQQ----------QPYDNSMGGYDP 368
            ...        .|:..|.|.|....|          ||...|..| ||
Human   336 AGDAFLTLRTLASLQPPPGGGCLQSQAQGSWQGATPQPATASPAG-DP 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_001259592.1	PBC	41..237	CDD:397732	144/212 (68%)
		homeodomain	239..299	CDD:238039	53/59 (90%)
PBX4	XP_011526622.1	PBC	18..226	CDD:281746	144/211 (68%)
		homeodomain	228..289	CDD:238039	54/60 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152651
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0774
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D348471at33208
OrthoFinder	1	1.000	-	-		FOG0000743
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11850
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X78
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.810