DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment exd and Meis1

DIOPT Version :9

Sequence 1:	NP_001259592.1	Gene:	exd / 32567	FlyBaseID:	FBgn0000611	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_006251591.1	Gene:	Meis1 / 686117	RGDID:	1585482	Length:	465	Species:	Rattus norvegicus

Alignment Length:	149	Identity:	44/149 - (29%)
Similarity:	72/149 - (48%)	Gaps:	24/149 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   240 RKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQ 304
            :||..|.|.|:.|:..:.:.||::||||||.|::||:..|:|:.||:|||.|.|   ::.:....
  Rat   274 KKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINAR---RRIVQPMI 335

  Fly   305 EEANLYAAKKAAGASPYSMAGPP-----------SGTTTPMMSPAPPQ-----DSMGYPMGSGGY 353
            :::|    :..:..:||:..|.|           .|...|.:...|.:     ..||..||...|
  Rat   336 DQSN----RAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSY 396

  Fly   354 DQ-QQPYDNSMGGYDPNLH 371
            .| |.|...:...:.|.:|
  Rat   397 TQAQMPPHPAQLRHGPPMH 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_001259592.1	PBC	41..237	CDD:397732
exd	NP_001259592.1	homeodomain	239..299	CDD:238039	26/58 (45%)
Meis1	XP_006251591.1	Meis_PKNOX_N	108..192	CDD:406806
		Homeobox_KN	290..329	CDD:399131	20/41 (49%)
		PABP-1234	<326..449	CDD:130689	19/97 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346176
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X78
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840