Protein Alignment exd and Pbx3

DIOPT Version :10

• Sequence 1: NP_523360.1
• Gene: exd / 32567
• FlyBaseID: FBgn0000611
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001101304.1
• Gene: Pbx3 / 311876
• RGDID: 1307198
• Length: 434
• Species: Rattus norvegicus
• Alignment Length: 412
• Identity: 276/412 - (66%)
• Similarity: 298/412 - (72%)
• Gaps: 62/412 - (15%)

  Fly     1 MEDPNRML---------AHT--GGM-MAPQGYGLSGQD-DGQNAGSENEVRKQKDIGEILQQIMS 52
            |:|.:|||         .|:  ||| :.|..:|..|.| ||         ||| |||:||.|||:
  Rat     1 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDG---------RKQ-DIGDILHQIMT 55

  Fly    53 ISEQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGV 117
            |::||||||||:||.|||||||||||||||||||||.||||..|||:|||||||||||||:||||
  Rat    56 ITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGV 120

  Fly   118 AGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACNEFTT 182
            :|||||||.||||:|||||.|.|      ||:||||||||||.|||||||.||||||||||||||
  Rat   121 SGPEKGGGSAAAAAAAAASGGSS------DNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTT 179

  Fly   183 HVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSK 247
            |||||||||||||||:||||||||.|||:||||||||||||||||||||||||||||||||||||
  Rat   180 HVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSK 244

  Fly   248 QASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAA 312
            ||:|||||||||||||||||||||||||:||.|||||||||||||||||||||||.|||||||||
  Rat   245 QATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAA 309

  Fly   313 KKAAGASPYSMAGPPSGTTTPMMSPAPPQD----SMGYPMGSG-------------------GYD 354
            |.|..|:....|...:..|.   ||..|..    |...| .||                   |.:
  Rat   310 KTAVTAAHAVAAAVQNNQTN---SPTTPNSGSSGSFNLP-NSGDMFMNMQSLNGDSYQGSQVGAN 370

  Fly   355 QQQPYD------NSMGGYDPNL 370
            .|...|      |..|||...|
  Rat   371 VQSQVDTLRHVINQTGGYSDGL 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_523360.1	PBC	42..237	CDD:461052	165/194 (85%)
		homeodomain	239..299	CDD:238039	56/59 (95%)
Pbx3	NP_001101304.1	PBC	45..234	CDD:461052	165/194 (85%)
		homeodomain	236..296	CDD:238039	56/59 (95%)