DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment exd and Tgif1

DIOPT Version :9

Sequence 1:	NP_001259592.1	Gene:	exd / 32567	FlyBaseID:	FBgn0000611	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001157547.1	Gene:	Tgif1 / 21815	MGIID:	1194497	Length:	305	Species:	Mus musculus

Alignment Length:	213	Identity:	51/213 - (23%)
Similarity:	74/213 - (34%)	Gaps:	76/213 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 RRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNI--- 300
            ||:|.|..|::.:||.::.|.|..|.||||:.|..|:::..::..||.|||.|.|.|...::
Mouse    69 RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRK 133

  Fly   301 --------------GKAQEEANLYAAKKAAGASP-------YSMAGPPSGTTTPMMSPAPPQD-- 342
                          .|..|.:::.||.......|       :|....|:.|....:||.||..
Mouse   134 DGKDPNQFTISRRGAKISEASSIEAAMGIKNFMPTLEESPFHSCVVGPNPTLGRPVSPKPPSPGS 198

  Fly   343 ---------------------SMGYPMGSG-GYDQQQ-------------PYDNSMGGYDPN--- 369
                                 |:..|:|.| ..|..|             |.|....|..||
Mouse   199 ILARPSVICHTTVTALKDGPFSLCQPIGVGQSTDVPQIAPSNFTDTSLVYPEDTCKSGPSPNPQS 263

  Fly   370 ------------LHQDLS 375
                        |:||.|
Mouse   264 GLFNTPPPTPPDLNQDFS 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_001259592.1	PBC	41..237	CDD:397732
exd	NP_001259592.1	homeodomain	239..299	CDD:238039	24/59 (41%)
Tgif1	NP_001157547.1	Homeobox_KN	86..125	CDD:283551	16/38 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842725
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840