DRSC/TRiP Functional Genomics Resources

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Protein Alignment exd and Pknox1

DIOPT Version :9

Sequence 1:NP_001259592.1 Gene:exd / 32567 FlyBaseID:FBgn0000611 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_057879.2 Gene:Pknox1 / 18771 MGIID:1201409 Length:436 Species:Mus musculus


Alignment Length:410 Identity:80/410 - (19%)
Similarity:139/410 - (33%) Gaps:123/410 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 MMAPQGYGLSGQDDGQNAGSENEVRKQKDIGEILQQIMSISE---QSLDEAQARKHTLNCHRMKP 75
            |||.|...:....|||......|::.::|..........:|.   :|.....|.|..:..|.:.|
Mouse     1 MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSDPDAEGVSPPPIESQTPMDADKQAIYRHPLFP 65

  Fly    76 --ALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQG 138
              ||....||         ::||..|........:|   |...|...||.|........      
Mouse    66 LLALLFEKCE---------QSTQGSEGTTSASFDVD---IENFVRKQEKDGKPFFCEDP------ 112

  Fly   139 GSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACNEFTTHVMNLLREQSRTR-------- 195
                        |..:...|..|:.:|:..||||..:.|.:|.:..:..|:.:..:.        
Mouse   113 ------------ETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPG 165

  Fly   196 ----PITPKEIERMV------------------------------------------QIIHKKF- 213
                |:..::|:..:                                          |::.:.. 
Mouse   166 SPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALS 230

  Fly   214 --------SSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEA 270
                    |.:|:||.|.    :.||......::.||....|.|:.::..:.:.|:.:|||:|:.
Mouse   231 PGTIRIQNSQLQLQLNQD----LSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDE 291

  Fly   271 KEELARKCGITVSQVSNWFGNKRIRY---------------KKNIGKAQEEANLYAAKKAAG--- 317
            |:::|.:..:|:.||:|||.|.|.|.               ||...:.:.....:....|:|   
Mouse   292 KKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQ 356

  Fly   318 ASPYSMA---GPPSGTTTPM 334
            |:|..:|   |.....|||:
Mouse   357 ATPSELAMSEGAVVTITTPV 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
exdNP_001259592.1 PBC 41..237 CDD:397732 41/263 (16%)
homeodomain 239..299 CDD:238039 21/74 (28%)
Pknox1NP_057879.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 23..50 4/26 (15%)
Meis_PKNOX_N 80..165 CDD:374576 18/105 (17%)
Homeobox_KN 277..316 CDD:368670 15/38 (39%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 401..436
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167842731
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X78
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.840

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