Protein Alignment exd and Pbx2

DIOPT Version :10

• Sequence 1: NP_523360.1
• Gene: exd / 32567
• FlyBaseID: FBgn0000611
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_059491.1
• Gene: Pbx2 / 18515
• MGIID: 1341793
• Length: 430
• Species: Mus musculus
• Alignment Length: 387
• Identity: 266/387 - (68%)
• Similarity: 294/387 - (75%)
• Gaps: 40/387 - (10%)

  Fly     9 AHTGGMMAPQGYGLSGQDDGQNAGSENEVRKQKDIGEILQQIMSISEQSLDEAQARKHTLNCHRM 73
            |..||...|.|    |.|.|..:|.....|.::|||:||||||:|::||||||||:||.||||||
Mouse    23 AEPGGPGEPPG----GGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRM 83

  Fly    74 KPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQG 138
            |||||||||||||||.||||::|||||.|||||||||||:||||||||||||.||||:|||||.|
Mouse    84 KPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGG 148

  Fly   139 GSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACNEFTTHVMNLLREQSRTRPITPKEIE 203
            |.    ..||:|||||||:||||||.|||.||||||||||||||||||||||||||||:.|||:|
Mouse   149 GV----SPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEME 209

  Fly   204 RMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSE 268
            |||.|||:|||:||||||||||||||||||||||||||||||||||:|:||||||||||||||||
Mouse   210 RMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSE 274

  Fly   269 EAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKA-----AGASPYSMAGPPS 328
            |||||||:||||||||||||||||||||||||||.|||||:||.|.|     .|.|..|...|||
Mouse   275 EAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVAQGGHSRTSSPTPPS 339

  Fly   329 GTTT----------------PMMS----PAPPQDSMGYPMGSGGYDQQQPYDNSMGG--YDP 368
            ...:                |.::    ||...:|:.:.||.|.|.     ||..||  |.|
Mouse   340 SAGSGGSFNLSGSGDMFLGMPGLNGDSYPASQVESLRHSMGPGSYG-----DNIGGGQIYSP 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_523360.1	PBC	42..237	CDD:461052	163/194 (84%)
		homeodomain	239..299	CDD:238039	56/59 (95%)
Pbx2	NP_059491.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		10/32 (31%)
		PBC	52..243	CDD:461052	163/194 (84%)
		PBC-A. /evidence=ECO:0000255|PROSITE-ProRule:PRU01322	55..134		67/78 (86%)
		PBC-B. /evidence=ECO:0000255|PROSITE-ProRule:PRU01322	137..243		90/109 (83%)
		homeodomain	245..305	CDD:238039	56/59 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..347		6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	375..430		10/27 (37%)