Protein Alignment exd and Meis2

DIOPT Version :10

• Sequence 1: NP_523360.1
• Gene: exd / 32567
• FlyBaseID: FBgn0000611
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: XP_011237639.1
• Gene: Meis2 / 17536
• MGIID: 108564
• Length: 559
• Species: Mus musculus
• Alignment Length: 324
• Identity: 79/324 - (24%)
• Similarity: 114/324 - (35%)
• Gaps: 104/324 - (32%)

  Fly   116 GVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEK---YEQAC 177
            |..||..||         .|||.|       ||:.|..      |...:..|..|.|   ....|
Mouse   250 GTPGPSSGG---------HASQSG-------DNSSEQG------ASETEADHLLLWKPMTDRTGC 292

  Fly   178 NEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLD----- 237
              .:..:....||:||....:|:.:|.::......|        :...||    ....||
Mouse   293 --VSVQMSREDREESREGKHSPQPLENIIIPCQPPF--------RGESEA----GGDGLDNSVAS 343

  Fly   238 -------------ARRKRRN-FSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNW 288
                         .|:|:|. |.|.|:.|:..:.:.||::||||||.|::||:..|:|:.||:||
Mouse   344 PGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNW 408

  Fly   289 FGNKRIRYKKNIGKAQEEANLYAAKKAAGASPYSMAGPPSGT----------------------- 330
            |.|.|.|..:.:......|........:..:.||..|.|.|:
Mouse   409 FINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDY 473

  Fly   331 ----------------TTPMMSPAPPQDSMGYPMGSGGYDQQQPYDNSM---GGYDPNLHQDLS 375
                            |.|.|:|.|.|...|.||.|  |....|:..:|   ||  |..|..::
Mouse   474 VSQGGPMGMGMAQPSYTPPQMTPHPTQLRHGPPMHS--YLPSHPHHPAMVMHGG--PPTHPGMT 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_523360.1	PBC	42..237	CDD:461052	26/123 (21%)
		homeodomain	239..299	CDD:238039	28/60 (47%)
Meis2	XP_011237639.1	Meis_PKNOX_N	129..213	CDD:465140
		Homeobox_KN	377..415	CDD:428673	20/37 (54%)