DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment exd and Meis1

DIOPT Version :9

Sequence 1:	NP_001259592.1	Gene:	exd / 32567	FlyBaseID:	FBgn0000611	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_034919.1	Gene:	Meis1 / 17268	MGIID:	104717	Length:	465	Species:	Mus musculus

Alignment Length:	149	Identity:	44/149 - (29%)
Similarity:	72/149 - (48%)	Gaps:	24/149 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   240 RKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQ 304
            :||..|.|.|:.|:..:.:.||::||||||.|::||:..|:|:.||:|||.|.|   ::.:....
Mouse   274 KKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINAR---RRIVQPMI 335

  Fly   305 EEANLYAAKKAAGASPYSMAGPP-----------SGTTTPMMSPAPPQ-----DSMGYPMGSGGY 353
            :::|    :..:..:||:..|.|           .|...|.:...|.:     ..||..||...|
Mouse   336 DQSN----RAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSY 396

  Fly   354 DQ-QQPYDNSMGGYDPNLH 371
            .| |.|...:...:.|.:|
Mouse   397 TQAQMPPHPAQLRHGPPMH 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_001259592.1	PBC	41..237	CDD:397732
exd	NP_001259592.1	homeodomain	239..299	CDD:238039	26/58 (45%)
Meis1	NP_034919.1	Meis_PKNOX_N	108..191	CDD:293102
Meis1	NP_034919.1	Homeobox_KN	290..329	CDD:283551	20/41 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842710
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X78
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840