Protein Alignment exd and pknox2

DIOPT Version :10

• Sequence 1: NP_523360.1
• Gene: exd / 32567
• FlyBaseID: FBgn0000611
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001120899.1
• Gene: pknox2 / 100151724
• XenbaseID: XB-GENE-853128
• Length: 468
• Species: Xenopus tropicalis
• Alignment Length: 329
• Identity: 65/329 - (19%)
• Similarity: 107/329 - (32%)
• Gaps: 141/329 - (42%)

  Fly    60 EAQARKHTLNCHRMKPALFSVLCEIKEKTV------------LSIRN-----TQEEEP---PDPQ 104
            :.:|.|..:..|.:.| |.::|.|..|:..            :.|.|     .||.:|   .||:
 Frog    65 QLEADKRAVYRHPLFP-LLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSEDPE 128

  Fly   105 LMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQE 169
               |||:::                                            |..|:.:|:..|
 Frog   129 ---LDNLMV--------------------------------------------KAIQVLRIHLLE 146

  Fly   170 LEKYEQACNEFTT----------HVMNLLREQ-----SRTRPITPKEIERMV------------- 206
            |||..:.|.:|..          |..||||..     |..:|......:.|:
 Frog   147 LEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSNSLHTQDMLQNSPNSMTGLSNN 211

  Fly   207 -------------------------------------------QIIHKKF--SSIQMQLKQSTCE 226
                                                       |::.:..  .:||:|..|...|
 Frog   212 PQGIVVPASALQQGNISMTTVNSSQVVSGGALYQPVAMVTSQGQVVTQAIPQGAIQIQNAQVNLE 276

  Fly   227 AVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGN 291
            ...:|.|....::.||....|.|:.|:..:.:.||.:|||:|:.|.::|.:..:|:.||:|||.|
 Frog   277 LTSLLDSEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFIN 341

  Fly   292 KRIR 295
            .|.|
 Frog   342 ARRR 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_523360.1	PBC	42..237	CDD:461052	43/269 (16%)
		homeodomain	239..299	CDD:238039	22/57 (39%)
pknox2	NP_001120899.1	Meis_PKNOX_N	95..180	CDD:465140	24/131 (18%)
		Homeobox_KN	307..345	CDD:428673	16/37 (43%)