Protein Alignment exd and pbx2

DIOPT Version :10

• Sequence 1: NP_523360.1
• Gene: exd / 32567
• FlyBaseID: FBgn0000611
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001122133.1
• Gene: pbx2 / 100101713
• XenbaseID: XB-GENE-484669
• Length: 422
• Species: Xenopus tropicalis
• Alignment Length: 410
• Identity: 271/410 - (66%)
• Similarity: 297/410 - (72%)
• Gaps: 71/410 - (17%)

  Fly    12 GGMMAPQGYGLSGQ-------------------DDGQNAGSENEVRKQKDIGEILQQIMSISEQS 57
            |.:|..:|.|:.|.                   |:|       |.||| |||:||||||:|::||
 Frog     5 GRLMQARGVGIPGHPIHGGPQTLTPHPMHEPPADNG-------EPRKQ-DIGDILQQIMTITDQS 61

  Fly    58 LDEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEK 122
            ||||||:||.|||||||||||||||||||||.|||||||||||.|||||||||||:|||||||||
 Frog    62 LDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRNTQEEEPVDPQLMRLDNMLLAEGVAGPEK 126

  Fly   123 GGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACNEFTTHVMNL 187
            |||.||||:|||||.|.|     .||:|||||||.||:|||||||.|||||||||||||||||||
 Frog   127 GGGSAAAAAAAAASGGVS-----PDNSIEHSDYRNKLSQIRQIYHAELEKYEQACNEFTTHVMNL 186

  Fly   188 LREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEI 252
            ||||||||||:||||||||.|||:||||||||||||||||||||||||||||||||||||||:|:
 Frog   187 LREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEV 251

  Fly   253 LNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKAAG 317
            |||||||||||||||||||||||:||||||||||||||||||||||||||.|||||:||.|.|..
 Frog   252 LNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVS 316

  Fly   318 ASPYSMAGPPSGTTTPMMSPAPPQDSMGYPMGSGGY-----------------------DQQQPY 359
            .:    .|..||..    ||..|..:     ||||.                       .|.:..
 Frog   317 VA----QGGHSGAN----SPTTPTSA-----GSGGSFNLSGSNDMFMAMQGLNGDSYPPSQVESL 368

  Fly   360 DNSMG-GYDPNL--HQDLSP 376
            .::|| ||..:|  :|..||
 Frog   369 RHTMGPGYSDSLSANQMYSP 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_523360.1	PBC	42..237	CDD:461052	168/194 (87%)
		homeodomain	239..299	CDD:238039	56/59 (95%)
pbx2	NP_001122133.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		8/44 (18%)
		PBC	46..236	CDD:461052	168/194 (87%)
		PBC-A. /evidence=ECO:0000255|PROSITE-ProRule:PRU01322	49..128		69/78 (88%)
		PBC-B. /evidence=ECO:0000255|PROSITE-ProRule:PRU01322	131..236		93/109 (85%)
		homeodomain	238..298	CDD:238039	56/59 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	319..341		10/30 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	353..422		9/36 (25%)