Protein Alignment eIF5 and eif5

DIOPT Version :9

• Sequence 1: NP_573098.1
• Gene: eIF5 / 32566
• FlyBaseID: FBgn0030719
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_001008209.1
• Gene: eif5 / 493571
• XenbaseID: XB-GENE-957969
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 468
• Identity: 230/468 - (49%)
• Similarity: 311/468 - (66%)
• Gaps: 44/468 - (9%)

  Fly     3 TVNVNRSVTDIFYRYKMPRLQAKVEGKGNGIKTVLVNMAEVARAIGRPATYPTKYFGCELGAQTL 67
            :|||||||:|.|||||||||.|||||||||||||:|||.:||:|:.||.|||||||||||||||.
 Frog     2 SVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQ 66

  Fly    68 FDHKNERFVVNGSHDVNKLQDLLDGFIRKFVLCPECDNPETNLTVSAKNQTISQSCKACGFHGLL 132
            ||.||:|::|||||:.|||||:|||||:||||||||:||||:|.|:.|.|||..||||||:.|:|
 Frog    67 FDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGYRGML 131

  Fly   133 KVNHKVNTFIVKNPPSLNPAAQGSSLTEGKRSRKQKQKNDNADGSMTNNSLANNSGGESDGGNGT 197
            ..|||:.|||:||||         ..|:....:|:|.|.             |..|.|.:.|:..
 Frog   132 DTNHKLCTFILKNPP---------ENTDSNAGKKEKDKK-------------NRKGKEKENGSAA 174

  Fly   198 NQASQTEAEISAAIPEKTA-KDDDDEGWSVDVSKEAIRARLQDLTDGAKGMTISDDYDKTEKERI 261
            |: ||...|:|.  |...| ::||||.|..|.:.||.|.|::::::.||.:|:|:|.:|..::|:
 Frog   175 NE-SQVLTELSP--PRVDADEEDDDEDWGEDTTAEAQRRRMEEISEHAKNLTLSEDLEKPVEDRV 236

  Fly   262 DIFYELVKDKRDKKQLDDVQTHKELVIEAERLDIINKAPLVLAELLFTENIIKDVQKNRPLLLRF 326
            :|.::.||.|:::..:|  .:.|:::.||||||:....||||:|:||.:.|...::|.|...|||
 Frog   237 NILFDFVKKKKEEGVID--SSDKDILAEAERLDVKAMGPLVLSEVLFDDKIRDQIKKYRRHFLRF 299

  Fly   327 TLNNPKAQRYLIGGVEQTVELHKGILMSKVAGIFKLFYDLDILDEAVILEWAQKVSKRHVSKNIA 391
            ..||.||||||:.|.|..|::|:..|:||:..|.|..||.|:|:|.||..|.:|.||::|||.:|
 Frog   300 CHNNKKAQRYLLHGFECVVDMHQSHLLSKIPHILKEMYDADLLEEEVIFSWVEKPSKKYVSKELA 364

  Fly   392 AEIHEKAMPFVLWLKNAEEESS---ESEEEEDDESEEDNYVSSAGQRGGQRVVQRGIPR--AVAG 451
            .:|..||.||:.|||.||||||   |.|||||||:.|..|..:.           .:|:  :|..
 Frog   365 KDIRAKADPFIKWLKEAEEESSGDDEEEEEEDDENIEVVYSKTV-----------SVPKVESVKS 418

  Fly   452 DEDDEDDVNIDDI 464
            ..|.:||::||.|
 Frog   419 PVDKDDDIDIDAI 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF5	NP_573098.1	eIF-5_eIF-2B	10..127	CDD:280114	89/116 (77%)
		W2_eIF5	254..408	CDD:211399	67/153 (44%)
eif5	NP_001008209.1	eIF-5_eIF-2B	9..128	CDD:376636	91/118 (77%)
		W2_eIF5	229..381	CDD:211399	67/153 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I2912
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49610
Inparanoid	1	1.050	435	1.000	Inparanoid score	I1657
OMA	1	1.010	-	-		QHG54429
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004050
OrthoInspector	1	1.000	-	-		oto103024
Panther	1	1.100	-	-	LDO	PTHR23001
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2797
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.070