DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF5 and eif2s2

DIOPT Version :9

Sequence 1:	NP_573098.1	Gene:	eIF5 / 32566	FlyBaseID:	FBgn0030719	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_997840.1	Gene:	eif2s2 / 324365	ZFINID:	ZDB-GENE-030131-3085	Length:	327	Species:	Danio rerio

Alignment Length:	138	Identity:	28/138 - (20%)
Similarity:	58/138 - (42%)	Gaps:	20/138 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KTVLVNMAEVARAIGRPATYPTKYFGCELGAQTLFDHKNERFVVNGSHDVNKLQDLLDGFIRKFV 98
            ||..||..::.:.:.|...:...:...|||.....|..|: .|:.|.....:::::|..:|:::|
Zfish   210 KTSFVNFTDICKLLHRQPKHLLVFLLAELGTSGSIDGNNQ-LVIKGRFQQKQIENVLRRYIKEYV 273

  Fly    99 LCPECDNPETNLTVSAKNQTISQSCKACGFHGLLKVNHKVNTFIVKNPPSLNPAAQGSSLTEGKR 163
            .|..|.:|:|.|....:...:  .|:.|        :.:.:...:|.         |.....|||
Zfish   274 TCHTCRSPDTILQKDTRLYFL--QCETC--------HSRCSVASIKT---------GFQAVTGKR 319

  Fly   164 SRKQKQKN 171
            ::.:.:.|
Zfish   320 AQLRAKAN 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF5	NP_573098.1	eIF-5_eIF-2B	10..127	CDD:280114	21/92 (23%)
eIF5	NP_573098.1	W2_eIF5	254..408	CDD:211399
eif2s2	NP_997840.1	eIF2B_5	193..302	CDD:214764	22/102 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1601
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810