DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Slc25A46a and Slc25a46

DIOPT Version :9

Sequence 1:	NP_573096.1	Gene:	Slc25A46a / 32564	FlyBaseID:	FBgn0030717	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001093985.1	Gene:	Slc25a46 / 291709	RGDID:	1305072	Length:	418	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	124/312 - (39%)
Similarity:	200/312 - (64%)	Gaps:	0/312 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 GVQWVSLVTENLLSHPFVVLRRQCQVYNASRRYHLHPFQLLPSIVHLHRRQGLTTLWKGVGSCLL 126
            |:...||.|||:|:||.:||||||||...:|.|||.||.::..:...::.||...||||:||..:
  Rat   104 GIGLASLFTENVLAHPCIVLRRQCQVNYHARHYHLTPFSVINIMYSFNKTQGPRALWKGMGSTFI 168

  Fly   127 VRGMTLAIDDFISKVTSWPKDVNSRTTLKRFGQHLLLKCISIGLVVPFYAASLVETVQSDIASEK 191
            |:|:||..:..||:.|..|::|:.:...|:.|:||||||::..:.:|||:|||:|||||:|..:.
  Rat   169 VQGVTLGAEGIISEFTPLPREVSQKWNPKQIGEHLLLKCLTYMVAMPFYSASLIETVQSEIIRDN 233

  Fly   192 PGLFDVFREGSLRLFYWSSPQKGRMLPAWALIGPSVSFGITKYLFNLVIRGVSSRIMRLRIKNSQ 256
            .|:.:..:||..|:.....|...|:||.::||.|:|..|:..|:.:.:|:.:...|::.:..:|.
  Rat   234 TGILECVKEGIGRVIGLGVPHSKRLLPLFSLIFPTVLHGVLHYIISSIIQKIVLLILKRKTCSSH 298

  Fly   257 DGQGGKYQDTTLEQQNADIYASLIAIITTEVMFFPFETILHRLQLQGTRTIIDNLDNGYDVVPIL 321
            ..:........|:....::.|:..|.:.::|:.:|.||:||||.:|||||||||.|.||:|:||.
  Rat   299 LAESTSPMQNMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVLPIN 363

  Fly   322 TNYQGVVDCYQTTIVSEGVSGLYKGFGAMILQFAAHVAVIKLTKWVVNQIVE 373
            |.|:|:.||..|....|||.|.||||||:|:|:..|..::::||.:.:.:::
  Rat   364 TQYEGMRDCVNTIKQEEGVFGFYKGFGAVIIQYTLHATILQITKIIYSTLLQ 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc25A46a	NP_573096.1	Mito_carr	277..360	CDD:278578	44/82 (54%)
Slc25a46	NP_001093985.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	46..96
		Solcar 1	96..187		38/82 (46%)
		Solcar 2	311..416		46/105 (44%)
		Mito_carr	317..402	CDD:395101	44/84 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348358
Domainoid	1	1.000	160	1.000	Domainoid score	I3958
eggNOG	1	0.900	-	-		E1_KOG2954
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14518
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3033
OMA	1	1.010	-	-		QHG48591
OrthoDB	1	1.010	-	-		D283554at33208
OrthoFinder	1	1.000	-	-		FOG0005765
OrthoInspector	1	1.000	-	-		otm45537
orthoMCL	1	0.900	-	-		OOG6_107935
Panther	1	1.100	-	-	LDO	PTHR21252
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4154
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770