Protein Alignment Cep164 and Cep164

DIOPT Version :10

• Sequence 1: NP_573095.1
• Gene: Cep164 / 32563
• FlyBaseID: FBgn0030716
• Length: 1246
• Species: Drosophila melanogaster
• Sequence 2: XP_038938279.1
• Gene: Cep164 / 363055
• RGDID: 1561243
• Length: 2053
• Species: Rattus norvegicus
• Alignment Length: 1370
• Identity: 264/1370 - (19%)
• Similarity: 478/1370 - (34%)
• Gaps: 390/1370 - (28%)

  Fly    13 STASAELTKSLPATP------------SSSSQGSSSVICEE----------------VFDEACFP 49
            |.:|.....|.||.|            |...|....|..||                ..:|:...
  Rat   870 SQSSNPKASSSPAAPGLDPGGDQPNRVSKKEQEEDPVEAEEEASREDSAAKEPKEPSALEESASD 934

  Fly    50 SSEEINEYASL--------------------IGIDPQKEPHLL------------YLAKEGLMAA 82
            :|||...:..|                    ||:..:...|||            :...:||...
  Rat   935 ASEESGIHEHLKDPQHSESGTSGPKSFLRLDIGLRGRVSEHLLDGNMPSPALGGGHWEAQGLGQE 999

  Fly    83 LPTDWKICYSEEKNGHYYHNTRTKESQWDHPLDAIYRDLVNQARQK-PLDTGSVGDNDDLSQLDS 146
            ...|.:...||.::.|      |:.|:.:.|...::    :||.:: ||.|           |:.
  Rat  1000 EQDDSRSSRSEPQSKH------TQVSEREQPRSTLH----SQATEEGPLRT-----------LEG 1043

  Fly   147 GIRSMQGIDDIPSPGPLPLNSLARKWSVASKASLFSSAKSRFLESGSKDMGRLHQLGFEVTKSKP 211
            ......|.|.:.||.||   |..::..|.|..:....|:.:  .|.::::| |.|...|.|:.|.
  Rat  1044 QPEGQPGKDSVASPAPL---SFLQREQVLSPPAFPERAEEK--HSQAEELG-LGQQEAEETEEKV 1102

  Fly   212 QIANKPAPTSQMNGKTDRSEENEGGTKPSGTVSMFQKAHRQFESDGYTSPSGVKGI--------- 267
            ::    :|:|.::.:...:|       |:.....|.:|             .:|||
  Rat  1103 EV----SPSSPVSPEVQTAE-------PAAPQKQFSEA-------------VLKGIEEGVTQELE 1143

  Fly   268 --------LRDSSITDISRRLDRLEPTVEGEDKKSVRFNLDQGQRGKSSPEETQSIKMTQAYKQN 324
                    |:...:..:..||.|.|...|.|:::..:...::.::.:...||.:.....:..::.
  Rat  1144 EDHRLLLELQKEKLQQLEERLCREEEEEEKEEEEEEKEEEEEEEKEEEEEEEKEEEGEEEEKEEK 1208

  Fly   325 EHSQSEDDDED----------------------VVVQGDDDDEDDDEDNDVIEDEDVDKDDREGA 367
            |..:.|:::|:                      ..:|...::|:.:|:..:.|:|    ..|...
  Rat  1209 EEEEEEEEEEEKEEKEEEHWLYQQKEKSLSLLKTQLQKAAEEEEKEEETQIREEE----SQRLAC 1269

  Fly   368 LNPW-PDNDEAIYNRNPFLSDANKTIPKTIPEVVKISGSGDTVSDKTKDTDAPKLFYDDTDSDSK 431
            |... ..:.||..|:   :....:|..:.:.|..:.....:..|.:.|...|.:...:..:::.:
  Rat  1270 LRAQVQSSTEAFENQ---IRAEQQTALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEER 1331

  Fly   432 GSSVRSFIINKSEQDSSL------LVGNNAFDLEELGRKHSYELEQLQLKSAQAPASDKSICSTS 490
            .:........::|::::|      |.|.....:..|.:|||.|||||              |  |
  Rat  1332 SAQAALRAEKEAEKEATLLQLREQLEGERREAVAGLEKKHSTELEQL--------------C--S 1380

  Fly   491 AFRANIADKEAQLQTDFEAIRRDHEAKLKRFRHEYDLRLTSHQHKLEEAFELQMEKYRVQLERQL 555
            :..|...:..:.||...|..::..||:|:......:.|  :|| |:.:..|     |..:|...|
  Rat  1381 SLEAKHREVISNLQKKIEGAQQKEEAQLQESLGRAEQR--THQ-KVHQVIE-----YEQELSSLL 1437

  Fly   556 QSKRTLMATEHKSRMDALQANH-EEILRDLER--------------ELHGEEELLRREHSSRLSQ 605
            :.||..:..||:.:||.::..| :|:....||              .|.||.|.|||.|...|..
  Rat  1438 RDKRQEVEREHERKMDKMKEEHWQEMAEARERYEAEERKQRADLLGHLTGELERLRRAHERELES 1502

  Fly   606 MREKFARELDAEKQRFREKGEERLYEKVRCEKRLLEDKYRCLKEKYVRLKTDVKLSLERRNRRRE 670
            :|::..::|:..::|.|:  :||..:.:..|   |..:.:.:|.:.      .:|:::..|.|:|
  Rat  1503 VRQEQDQQLEDLRRRHRD--QERKLQDLEAE---LSSRTKDVKARL------AQLNVQEENMRKE 1556

  Fly   671 AQMAPQHNHTNSTKSTNSGTEMERSMERYYKPQSGNSDNRSLSYSDQAIAGEAIVKPCPVPHKSQ 735
            .|:...... .:.......|...|.:|...|..:...::                       |.|
  Rat  1557 KQLLLDAQR-QAALEKEEATATRRHLEEAKKEHTHLLES-----------------------KQQ 1597

  Fly   736 LTKSYN---IRQLQLQDDNTSISQSDTTLSNTYNNGRYGPFLKSASGVLSARTASDNGNSSRDGV 797
            |.::.:   :|:::|:      ||.|.              |::.|..|....:|
  Rat  1598 LRRAIDDLRVRRVELE------SQVDQ--------------LQTQSQRLQKHVSS---------- 1632

  Fly   798 VAAVATQSNLERNNNSNQIKESTGINRIVFSRTKSASTSRLNSDTSYKGERPCTPVENLRHQLQK 862
                 .::.::|..|.  :||            .:|.|:      :.....|...:|:||..|..
  Rat  1633 -----LEAEVQRKQNI--LKE------------MAAETN------APPHPEPGLHIEDLRKSLGT 1672

  Fly   863 LEALEDQFPENTLDAPYHLRYPFTDISIKPNGVGSELEFFKHRIHLERDSVRRAKESLRTQRTNF 927
            .|..|..                :.:|:...|:...::..:|.:..|..:||.|||.|..|..:.
  Rat  1673 NENQEVS----------------SSLSLSKEGIDLSMDSVRHFLSAEGVAVRSAKEFLVRQTRSM 1721

  Fly   928 RLRQREI--GQQRKITALSPKHSIDQ--------------LIQEEKELTEMEVNLHRTRSLLGEK 976
            |.||..:  .||.....|:....:|:              |.:|.|.|.||:..:.:...||.:|
  Rat  1722 RRRQTALKAAQQHWRHELASAQEVDEDLPGTKVLENVRKNLDEETKHLDEMKSAMRKGHDLLKKK 1786

  Fly   977 IIRLRHLEQSLLRIYEKEKSILDLGTMDDAATLSDLSSHSSSGFSS------TDLASAADFHKKK 1035
            ..:|..||.|||.....|.::...........|||:...||..|.|      |...::||  ..|
  Rat  1787 EEKLNQLESSLLEEVSDEDTLKGSSIKKVTFDLSDMDDLSSESFESCPLLHITPTPNSAD--PNK 1849

  Fly  1036 DYYQQESNECIENLEILNAEIREILDIFGQKQYQQQHDQTASGIP-------------ILSPRDL 1087
            .:|...|      |:.:::|:..:|.:.|....|......:|..|             ||:|.
  Rat  1850 IHYLSSS------LQRISSELNGVLSVLGSLNSQPLPQGLSSQPPPPLLTSSLRSSKNILAPA-- 1906

  Fly  1088 GWSQVLKHQHSGTQNFSLSDDI---------EGGGAVHIPHSIPTLAD--RLETYRQLAAGRMQS 1141
                    ..|.|:..|||...         .|.|....|.|.....|  .||.:|:.....:..
  Rat  1907 --------YSSQTKPSSLSSMTPTSTQWAWDPGQGTKLSPSSSSQTVDDFLLEKWRKYFPTGIPL 1963

  Fly  1142 SMGAAILTANTI----VSQSPRAVNYTTCLVERTRDL---------RNWLRQAKNEHDFLVQHGI 1193
            |.|:.....|.:    ||:....:..:...|.:|..:         |.||...:|:....:...:
  Rat  1964 SSGSPPPPENKLGYVSVSEQLHLLQRSHSRVPKTDSISIQSMIESNRKWLEHFRNDPKVQLFSSV 2028

  Fly  1194 PSGQT 1198
            |...|
  Rat  2029 PKSTT 2033

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cep164	NP_573095.1	WW	83..113	CDD:459800	6/29 (21%)
		DUF5401	<498..>678	CDD:375164	47/194 (24%)
Cep164	XP_038938279.1	WW	58..87	CDD:459800
		Smc	1285..>1805	CDD:440809	109/545 (20%)