Protein Alignment Cep164 and Cep164

DIOPT Version :10

• Sequence 1: NP_573095.1
• Gene: Cep164 / 32563
• FlyBaseID: FBgn0030716
• Length: 1246
• Species: Drosophila melanogaster
• Sequence 2: XP_006510196.1
• Gene: Cep164 / 214552
• MGIID: 2384878
• Length: 2034
• Species: Mus musculus
• Alignment Length: 1223
• Identity: 255/1223 - (20%)
• Similarity: 437/1223 - (35%)
• Gaps: 376/1223 - (30%)

  Fly    12 SSTASAELTKS-----LPATP-----SSSSQGSSSVICEEVFDEACFPSSEEINEYASLIGIDP- 65
            ||.|||..:||     .|..|     :|..:.|||.:..|:......||.....:.|.    ||
Mouse   844 SSVASANGSKSQGRGASPWNPQKENENSDPKASSSQMAPELDPGGDQPSRASKKQQAE----DPV 904

  Fly    66 -------------QKEPHLLYLAKEGLMAALPTDWKICYSEEKNGHYYHNTRTKESQWDHP---- 113
                         .|||      ||.  :||.....:....|.:|| ..:.|...|:...|
Mouse   905 QAGKEGECRRESAAKEP------KEA--SALENTSDVSEESEIHGH-LKDARHSGSEASGPKSFL 960

  Fly   114 -LDAIYRDLVNQARQKPLDTGSVGDNDDLSQ-LDSGIRSMQGIDDIPSPGPLPLNSLARKWSVAS 176
             ||..:|..:::         .:.|.|.||. |..|....||:|......        .|.|:|.
Mouse   961 GLDLGFRSRISE---------HLLDGDTLSPVLGGGHWEAQGLDQEEQDD--------SKSSIAE 1008

  Fly   177 KASLFSSAKSR-----FLESGSKDMGRLHQL-GFEVTK-----SKPQIANKPAPTSQMNGKTDRS 230
            ..|..:....|     .|.|.:.:.|.|..| |....|     .|..:|: |||.|.:
Mouse  1009 PQSKHTQGSEREHLQSSLHSQATEEGPLQTLEGQPEWKEAEGPGKDSVAS-PAPLSLL------- 1065

  Fly   231 EENEGGTKPSGTVSMFQKAHRQFESDGYTSPSG----VKGILRDSSITDISRRLDRLEPT----- 286
             :.|....|..:....::.|.|.|..|...|..    .|..:..||  .:|..:...||.
Mouse  1066 -QREQVLSPPASPERAEEKHSQAEELGLEQPEAEETEEKVAVCPSS--PVSPEVQTAEPAAPQKL 1127

  Fly   287 -----VEGEDKKSVRFNLDQGQR-----GKSSPEETQSIKMTQAYKQNEHSQSEDDDEDVVVQGD 341
                 ::|       ..|::.||     .|..|::.:.....:..::.|..:.|.:||:...:.:
Mouse  1128 FSEAILKG-------MELEEDQRLLLEFQKEKPQQLEERLWREEEEKEEGEEEEKEDEEEEGEEE 1185

  Fly   342 DDDEDDDEDNDVIEDEDVDKDDREGALNPWPDNDEAIYNRNPFLSDANKTIPKTIPEVVKISGSG 406
            :::|:.:|:.:..|:|:|.:                :|.:.      .|::.....::.|.:...
Mouse  1186 EEEEEKEEEEEEEEEEEVCQ----------------LYQQK------EKSLSLLKAQLQKATAEE 1228

  Fly   407 DTVSDKTK--DTDAPKLFYDDTDSDSKGSSVRSFIINKSEQDSSL-LVGNNAFDLEE-----LGR 463
            ....::||  :.::.:|........|:..:..:.|  ::||.::| .:...|..|::     |.:
Mouse  1229 KEKEEETKIREEESRRLVCLRAQVQSRTEAFENQI--RTEQQAALQRLREEAETLQKAERASLEQ 1291

  Fly   464 KHSYELEQLQLKSAQAPASDKSICSTSAFRA-NIADKEA---QLQTDFEAIRRDHEAKLKRFRHE 524
            |....||||:   .|..|.::|  :.:|.|| ..|:|||   ||:...|..|::..|.|:: :|.
Mouse  1292 KSRRALEQLR---EQLEAEERS--AQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEK-KHS 1350

  Fly   525 YDLR-------------LTSHQHKLEEAFEL---------------------QMEKYRVQLERQL 555
            .:|.             ::|.|.|:|.|.:.                     |:.:|..:|...|
Mouse  1351 AELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLL 1415

  Fly   556 QSKRTLMATEHKSRMDALQANHEEILRDL-------ERE--------LHGEEELLRREHSSRLSQ 605
            :.||..:..||:.:||.::..|.:.:.|.       ||:        |.||.|.|||.|...|..
Mouse  1416 RDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELES 1480

  Fly   606 MREKFARELDAEKQRFREKGEERLYE-KVRCEKRLLEDKYRC----LKEKYVRLKTDVKLSLERR 665
            ||::..::|:..::|.|:. |.:|.: :|....|..:.|.|.    ::|:.:|.:..:.|..:|:
Mouse  1481 MRQEQDQQLEDLRRRHRDH-ERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQ 1544

  Fly   666 N--RRREAQMAPQH------NHTN--STKSTNSGT---------EMERSMERYYKPQSGNSDNRS 711
            .  .|.||....||      .||:  .||.....|         |:|..:: ..:.||.......
Mouse  1545 AALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVD-LLQAQSQRLQKHL 1608

  Fly   712 LSYSDQA---------IAGEAIVKPCPVP--HKSQLTKSYNIRQLQLQDDNTSISQSDTTLSNTY 765
            .|...:.         :|.|....|.|.|  |...|.||.:..:.|....:.|:|:.:..||
Mouse  1609 SSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLS--- 1670

  Fly   766 NNGRYGPFLKSASGVLSARTASDNGNSSRDGVVAAVATQSNLERNNNSNQIKESTGINRIVFSRT 830
                    ::|....|||           :||..         ||.....::::..:.|
Mouse  1671 --------MESVRQFLSA-----------EGVAV---------RNAKEFLVRQTRSMRR------ 1701

  Fly   831 KSASTSRLNSDTSYKGERPCTPVENLRHQLQKLEALEDQFPENTLDAPYHLRYPFTDISIKPNGV 895
                     ..|:.|..:     ::.||:|...:.:::..|
Mouse  1702 ---------RQTALKAAQ-----QHWRHELASAQEVDEDLP------------------------ 1728

  Fly   896 GSELEFFKHRIHLERDSVRRAKESLRTQRTNFRLRQREIGQQRKITALSPKHSIDQLIQEEKELT 960
            |:|:                                  :|..||           .|.:|.:.|.
Mouse  1729 GTEV----------------------------------LGNMRK-----------NLNEETRHLD 1748

  Fly   961 EMEVNLHRTRSLLGEKIIRLRHLEQSL---------LRIYEKEKSILDLGTMDDAATLSDLSSHS 1016
            ||:..:.:...||.:|..:|..||.||         |:....:|...||..|||   ||..|..|
Mouse  1749 EMKSAMRKGHDLLKKKEEKLIQLESSLQEEVSDEDTLKGSSIKKVTFDLSDMDD---LSSESLES 1810

  Fly  1017 SSGFSSTDLASAADFHKKKDYYQQESNECIENLEILNAEIREILDIFGQKQYQ 1069
            |.....|...::||  ..|.:|...|      |:.:::|:..:|::.|....|
Mouse  1811 SPVLHITPTPTSAD--PNKIHYLSSS------LQRISSELNGVLNVLGSLNSQ 1855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cep164	NP_573095.1	WW	83..113	CDD:459800	6/29 (21%)
		DUF5401	<498..>678	CDD:375164	59/244 (24%)
Cep164	XP_006510196.1	WW	58..87	CDD:459800
		PHA03247	<325..740	CDD:223021
		Smc	1263..>1619	CDD:440809	106/449 (24%)
		EnvC	1541..>1789	CDD:443969	37/258 (14%)