Protein Alignment mmd and si:ch1073-396h14.1

DIOPT Version :10

• Sequence 1: NP_001285311.1
• Gene: mmd / 32561
• FlyBaseID: FBgn0259110
• Length: 1484
• Species: Drosophila melanogaster
• Sequence 2: XP_689465.6
• Gene: si:ch1073-396h14.1 / 560975
• ZFINID: ZDB-GENE-070705-6
• Length: 683
• Species: Danio rerio
• Alignment Length: 672
• Identity: 162/672 - (24%)
• Similarity: 256/672 - (38%)
• Gaps: 178/672 - (26%)

  Fly     9 ILIIAQLCVFVTSAGEADYTLDDSFWNEESPVGEVERLLKEYR---QNQELVRRIGGHYYQIIYP 70
            :|..|::|:.:       |.|....:.|.|..  :.:.:|.|.   .::|||::   |.::|
Zfish     5 LLNAARICLLI-------YILSRGHFTEASQA--ISKYIKHYEGLSYDRELVKQ---HQHRI--- 54

  Fly    71 VQLRHHEKMGISTREVSLPKPGQRPRPHDDSGFNRGRTKKHFHRTSLLIKAFNHKFRLDLELNSQ 135
                        .|:.:   |.::....|.|.|.|   :.|...|..:...|...|::..|..||
Zfish    55 ------------RRDAN---PNKQDLHLDFSAFQR---EFHLRLTPDVNNGFTEDFKVQSENESQ 101

  Fly   136 LLSPNIQQKHYHVGGYLVDGNRHDIEHCYYHGTVKDYPGASAAFHTCNG------VSGVIHIGNE 194
            ::                     |:.| .|.|.::|...:|     |.|      ..|.|...|.
Zfish   102 MV---------------------DLSH-IYSGVLEDDSKSS-----CQGSVLEGQFEGSITTSNG 139

  Fly   195 TFVIHPF--YGGDLSKHPHVIFEARTKANKGCANSGNLDSWRLSRRTKHLSAGVAGV--VEEIL- 254
            ||.:.|.  |....|.|..:|:           :..::|...|  |:.|  ||..|.  ::.:|
Zfish   140 TFYVEPIERYKTTHSDHHSIIY-----------HEDDVDDTPL--RSGH--AGFCGAERLQNLLQ 189

  Fly   255 ----QAGVGRNKRDVREATKYIETAIIVDKAMFDKRNGSTRAEVIHDAIQVANIADLY------- 308
                |..|.|:||.|.::.......:..|...: ||.||..|.|...|..:..:.|:|
Zfish   190 NHQEQIPVSRSKRKVDQSKTSCLLHLHTDHRYY-KRFGSIEAIVAQVASYMKAVNDVYDKANFDG 253

  Fly   309 FRTLNTRVSVVYIETWGKNQAVIDGSKDIS-------KAISNFNDYTSRNLFQIERDTTQLLTGE 366
            ...:|.:|..:.:.|      ..|.|..||       |.:|.|:: |:.|.|.:    :.|||..
Zfish   254 IELINFKVKFLTVIT------EEDPSSPISVTHVGPEKLLSLFSE-TNWNDFCL----SYLLTDR 307

  Fly   367 TFAG--GEAGMAVPET---VCTPRAV----------GISVDVNVYEPHLLAG----TMAHMIGHN 412
            .|:|  |.|.....:.   :|:...:          |: |.:..|..:|...    |.||.:||:
Zfish   308 DFSGVLGLAWEGKADNWGGICSKMILKSGRNCSHNTGL-VTLQTYGHYLSTKHVHLTFAHELGHS 371

  Fly   413 IGMGHDDGREECFCRDWH-----GCIM----AQSIVGQENVQPYKFSECSKKDYIDALRTGHGLC 468
            :|..||   |...|.|..     |..:    |.|.: :||..  |||.||.:.....|......|
Zfish   372 LGAPHD---ENSNCGDLEVTSGKGRFLMFPKAASRI-EENSD--KFSPCSLRHMSHLLNVKKDTC 430

  Fly   469 LLNKPNEIELRRNCGNKVVEEDEECDCGTFEECALDQCC------DGITCKLKSEAQC--ASGAC 525
            .::....|     |||::|||.||||.|..:.   |.||      .||.|:||...||  :.|.|
Zfish   431 FVDSDQPI-----CGNRIVEEGEECDVGHDDS---DPCCHSSKEPSGIECRLKLGKQCSPSQGLC 487

  Fly   526 CD-QCRLRPKDYICRDSNNECDLPEYCDGEIGQCPSDVFKKNGSPCGL-SKTGISGYCFQGYCPT 588
            |: ||..:....:| :.|:||.....|.|....||....|.:.:.|.. ::...||.|....|..
Zfish   488 CNSQCVFKKAGLMC-EGNSECRNKSVCAGSSAVCPEPPSKPDMTICSNGTRVCSSGECGLSLCAL 551

  Fly   589 LSL-QCEAIWGYGGSAADRQCY 609
            .:: ||:.    .|.:...:|:
Zfish   552 HNMVQCDC----PGQSKTEKCH 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mmd	NP_001285311.1	Pep_M12B_propep	104..214	CDD:460254	25/117 (21%)
		ZnMc_adamalysin_II_like	270..471	CDD:239797	58/242 (24%)
		Disintegrin	488..561	CDD:459709	30/81 (37%)
		ACR	566..713	CDD:214743	9/46 (20%)
si:ch1073-396h14.1	XP_689465.6	Pep_M12B_propep	47..161	CDD:460254	33/164 (20%)
		ZnMc	209..438	CDD:469599	58/247 (23%)
		Disintegrin	445..523	CDD:459709	30/81 (37%)