Protein Alignment mmd and Adam9

DIOPT Version :10

• Sequence 1: NP_001285311.1
• Gene: mmd / 32561
• FlyBaseID: FBgn0259110
• Length: 1484
• Species: Drosophila melanogaster
• Sequence 2: XP_063131318.1
• Gene: Adam9 / 290834
• RGDID: 621473
• Length: 909
• Species: Rattus norvegicus
• Alignment Length: 959
• Identity: 283/959 - (29%)
• Similarity: 403/959 - (42%)
• Gaps: 182/959 - (18%)

  Fly    65 YQIIYPVQLRHHEKMGISTREVSLPKPGQRPRPHDDSGFNRGRTKKHFHRTSLLIKAFNHKFRLD 129
            |:|:.|.:|....      ||...|...|                     .|.:|:|...:..:.
  Rat    43 YEIVTPWRLSRER------REALRPSSKQ---------------------ISYVIQAQGKQHIIH 80

  Fly   130 LELNSQLLSPNIQQKHYHVGGYLVDGNRHDIEHCYYHGTVKDYPGASAAFHTCNGVSGVIHIGNE 194
            ||.|:.||..:.....|...|.|:..:.:...||:|.|.|:..|.::.|...|.|:.|::|:.|.
  Rat    81 LERNTDLLPNDFVVYTYDEEGSLLSDHPNVQSHCHYRGYVEGVPNSTVAVSACFGLRGLLHLENA 145

  Fly   195 TFVIHPFYGGDLSKHPHVIFEA----RTKANKGCANSGNLDSWRLSRRTKHLSAGVAGVVEEILQ 255
            :|.|.|.:..  |...||.:..    :.....|.:|.............:|.|      |.::|
  Rat   146 SFGIEPLHNS--SHFEHVFYPMDDVHQEPLRCGVSNRDTEQEATQGEEEEHPS------VTQLL- 201

  Fly   256 AGVGRNKRDVREATKYIETAIIVDKAMFDKRNGSTRAEVIHDAIQVANIADLYFRTLNTRVSVVY 320
                |.:|.|...|:|:|..|:|||..::.. |..:..|..:.|::||..|..:..||.|:.:|.
  Rat   202 ----RRRRAVLPQTRYVELFIVVDKERYNMM-GRNQTAVREEMIRLANYLDSMYIMLNIRIVLVG 261

  Fly   321 IETWGKNQA--VIDGSKDISKAISNFNDYTSRNLFQIER---DTTQLLTGETFAGGEAGMAVPET 380
            :|.|.....  :|.|:.|:   :.||..:  |..|.|.|   |:.||:..:.| ||.||||...|
  Rat   262 LEIWTDRNPINIIGGAGDV---LGNFVQW--REKFLITRRRHDSAQLVLKKGF-GGTAGMAFVGT 320

  Fly   381 VCTPRAVGISVDVNVY---EPHLLAGTMAHMIGHNIGMGHDDGREECFCRDWHGCIMAQSIVGQE 442
            ||:....|   .:||:   .....|..:||.:|||:||.||||| ||||.. ..|||.....|..
  Rat   321 VCSRSHAG---GINVFGQITVETFASIVAHELGHNLGMNHDDGR-ECFCAA-KSCIMNSGASGSR 380

  Fly   443 NVQPYKFSECSKKDYIDALRTGHGLCLLN--KPNEIELRRNCGNKVVEEDEECDCGTFEECALDQ 505
            |     ||.||.:|:........|.||||  ||:|.....:||||:|:..|||||||.:||.||.
  Rat   381 N-----FSSCSAEDFEKLTLNKGGSCLLNIPKPDEAYSAPSCGNKLVDPGEECDCGTPKECELDP 440

  Fly   506 CCDGITCKLKSEAQCASGACCDQCRLRPKDYICRDSNNECDLPEYCDGEIGQCPSDVFKKNGSPC 570
            ||:|.||||||.|:||.|.||..|:..|...:||...:|||:||||:|....||.|||.:||.||
  Rat   441 CCEGSTCKLKSFAECAYGDCCKDCQFLPGGSMCRGKTSECDVPEYCNGSSQFCPPDVFIQNGYPC 505

  Fly   571 GLSKTGISGYCFQGYCPTLSLQCEAIWGYGGSAADRQCYEQFNSKGSINGHCGRDANEHYIKCEP 635
            ..||    .||:.|.|.....||:.|:|....||.|.|:.:.||||...|:|| .:..:|..|..
  Rat   506 WNSK----AYCYNGVCQYYDAQCQVIFGSKAKAAPRDCFIEVNSKGDRFGNCG-VSGSNYKTCAT 565

  Fly   636 ENVQCGTLQCKDGERQPVNDGIDQLYSRTIISIKGQEFECKATSGQVGSNSYPEHGLVKDGTPCG 700
            .|..||.|||::.:..||...:.     .||....:..:|.....|:||: .|:.|:|.:||.|.
  Rat   566 GNALCGKLQCENVQEMPVFGIVP-----AIIQTPSRGTKCWGVDFQLGSD-VPDPGMVNEGTKCD 624

  Fly   701 DNLICLNQTCVSLFPHVDQTKCPANSQGLECSEHGVCTNTNRCFCDMGWGGNDCSSVVLLTTALP 765
            ...||.|..||:  ..|....|  :.|| :|..||||.:...|.|:.||....|.
  Rat   625 AGKICRNFQCVN--ASVLNYDC--DIQG-KCHGHGVCNSNKNCHCEDGWAPPHCD---------- 674

  Fly   766 TEALPTPENTIKMEKKETPYGTSDQNRISTLTMVIILTVIVKCVFISFA---TLAVCYRRKTTTL 827
                 |......::...|....|...|...|....::..:|...|..|.   .|...:|:|.:.:
  Rat   675 -----TKGYGGSVDSGPTYNAKSTALRDGLLVFFFLIIPLVAAAFFLFIKRDELRKTFRKKRSQM 734

  Fly   828 K------------YDPPYSKKP----------------------IAKSYGGAA-----TAPNHHS 853
            .            .||..|:.|                      :::..||.:     .:|:|.|
  Rat   735 SDGRNQANASRPPGDPSVSRPPGGPSVSRPPGGPNVSRPPGGPNVSRPPGGPSVSRPPVSPHHVS 799

  Fly   854 VEEVSLDG-----------SSKLVYANQTGFR--DKG-IHGRRYTTCGEDDQSHAEKGILKKHGY 904
            ....|.|.           ||.:....|||.|  .:| .|......|..|.|...:|..::
  Rat   800 PVTPSRDAIRFIKNCLLLCSSVVHLKTQTGARRVSRGDTHPYCAYNCRFDLQFQIQKRKIQ---- 860

  Fly   905 GLVHGEQLKDKWGDDNQSDNLELITQDGTLASTSGGAAASEVERTLKSL 953
                      ||......||.       .|.:..||   .::|.|.:.|
  Rat   861 ----------KWLHSLNLDNY-------MLGNIEGG---PQIEGTSRGL 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mmd	NP_001285311.1	Pep_M12B_propep	104..214	CDD:460254	29/109 (27%)
		ZnMc_adamalysin_II_like	270..471	CDD:239797	73/208 (35%)
		Disintegrin	488..561	CDD:459709	40/72 (56%)
		ACR	566..713	CDD:214743	52/146 (36%)
Adam9	XP_063131318.1	None