Sequence 1: | NP_001285311.1 | Gene: | mmd / 32561 | FlyBaseID: | FBgn0259110 | Length: | 1484 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001101.1 | Gene: | ADAM10 / 102 | HGNCID: | 188 | Length: | 748 | Species: | Homo sapiens |
Alignment Length: | 747 | Identity: | 173/747 - (23%) |
---|---|---|---|
Similarity: | 251/747 - (33%) | Gaps: | 234/747 - (31%) |
- Green bases have known domain annotations that are detailed below.
Fly 60 IGGHYYQIIYPVQ--LRHHEKMGISTREVSLPKPGQRPR---PHDDSGFNRGRTKKHFHRTSLLI 119
Fly 120 KAFNHKFRLDLELNSQLLSPNIQQK--HYHVGGYLVDGNRHDIEHCYYHGTVKDYPGASAAFHTC 182
Fly 183 NGVSGVIHIGNETFVIHP---------------FYGGDLSKHPHVIFEARTKANKGCANSGNLDS 232
Fly 233 WRLSRRTKHLSAGVAGVVEEILQ------AGVG----RNKRDVREATK-----YIETAIIVDKAM 282
Fly 283 FDKRNGSTRAEVIHDAIQVANIADLY-------FRTLNTRVSVVYIETWGKNQAVIDGSKD---- 336
Fly 337 -------ISKAI-----SNFNDYTSRNLFQIERDTTQLLTGETFAGGEAGMAVPETVCTPRAV-- 387
Fly 388 ---------GISVDVNVYEPHLLAG----TMAHMIGHNIGMGHDDGREECFCRDWHGCIMAQS-I 438
Fly 439 VGQENVQPY---------------KFSECSKKDYIDALRTGHGLCLLNKPNEIELRRNCGNKVVE 488
Fly 489 EDEECDCGTFEECALDQCC------DGITCKLKSEAQC--ASGACCD-QCRLRPKDYICRDSNNE 544
Fly 545 CDLPEYCDGEIGQCPSDVFKKNGSPCGLSKTGISGYCFQGYCPTLSLQCEAIWGYGGSAADRQCY 609
Fly 610 EQFNSKGSINGHCGRDANEHYIKCEPENVQCGTLQCKDGERQPVNDGIDQLYSRTIISIKGQEFE 674
Fly 675 CKATSGQVGSNSYPEHG-----LVKDGTPCGD 701 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
mmd | NP_001285311.1 | Pep_M12B_propep | 106..213 | CDD:279848 | 25/123 (20%) |
Reprolysin | 270..473 | CDD:279729 | 56/261 (21%) | ||
ZnMc_adamalysin_II_like | 270..471 | CDD:239797 | 56/259 (22%) | ||
Disintegrin | 488..562 | CDD:278623 | 32/82 (39%) | ||
ACR | 566..713 | CDD:214743 | 22/141 (16%) | ||
ADAM10 | NP_001101.1 | Pep_M12B_propep | 46..156 | CDD:396235 | 25/129 (19%) |
Cysteine switch. /evidence=ECO:0000250 | 171..178 | 4/11 (36%) | |||
ZnMc_TACE_like | 220..459 | CDD:239798 | 55/263 (21%) | ||
DISIN | 466..545 | CDD:214490 | 31/80 (39%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 704..748 | ||||
SH3-binding. /evidence=ECO:0000255 | 708..715 | ||||
SH3-binding. /evidence=ECO:0000255 | 722..728 | ||||
Interaction with AP2A1, AP2A2 and AP2M1. /evidence=ECO:0000250|UniProtKB:O35598 | 734..748 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165146056 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D162519at2759 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.850 |