Protein Alignment Rrp47 and C1D

DIOPT Version :10

• Sequence 1: NP_573092.1
• Gene: Rrp47 / 32558
• FlyBaseID: FBgn0030711
• Length: 159
• Species: Drosophila melanogaster
• Sequence 2: NP_006324.1
• Gene: C1D / 10438
• HGNCID: 29911
• Length: 141
• Species: Homo sapiens
• Alignment Length: 131
• Identity: 40/131 - (30%)
• Similarity: 58/131 - (44%)
• Gaps: 15/131 - (11%)

  Fly     1 MAQENQAVDNGLPCNAYLDTSLREDENMQHILKTF--YSSIELLEADTEKALALQAERTLNTNEQ 63
            ||.|....|..:..:.||.........:..:|||.  .|..|||:             .|:..||
Human     1 MAGEEINEDYPVEIHEYLSAFENSIGAVDEMLKTMMSVSRNELLQ-------------KLDPLEQ 52

  Fly    64 IKLDSYLVYLNSTLFFIYLKLQGEDASNHAVMHDLRRTRDLLARDKKINDALAAPRLDMPAAKRF 128
            .|:|....|..:::|::||..||.:...|.|..:|.|.|..:.|.|:|.|...|.:||..||.||
Human    53 AKVDLVSAYTLNSMFWVYLATQGVNPKEHPVKQELERIRVYMNRVKEITDKKKAGKLDRGAASRF 117

  Fly   129 I 129
            :
Human   118 V 118

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rrp47	NP_573092.1	Sas10_Utp3	26..107	CDD:461123	23/82 (28%)
C1D	NP_006324.1	Required for transcriptional repression. /evidence=ECO:0000250	1..100		31/111 (28%)
		Sas10_Utp3	27..96	CDD:461123	23/81 (28%)
		Interaction with NR1D1. /evidence=ECO:0000250	50..100		17/49 (35%)
		Interaction with NCOR1 and NCOR2. /evidence=ECO:0000250	100..141		9/19 (47%)