Protein Alignment CG8924 and KBTBD4

DIOPT Version :10

• Sequence 1: NP_573091.1
• Gene: CG8924 / 32557
• FlyBaseID: FBgn0030710
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001305645.1
• Gene: KBTBD4 / 55709
• HGNCID: 23761
• Length: 567
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 56/248 - (22%)
• Similarity: 107/248 - (43%)
• Gaps: 28/248 - (11%)

  Fly    14 SHLGSIGAAFPQL-LAGQRFVDVTLACEGQQVHCHRLVLAACSTYFEAILAEHPCK-HPVIILPR 76
            ||.|.:.....:| |..:.|.|||::.||::...|||||:|.|.:|.::...:..: |..:|:.:
Human    74 SHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIVLQ 138

  Fly    77 EIKLWEIQALVDFMYKGEVNVTQAGLGQLLRCAEQLQIRGLYGSEAPINYKKLQQAS-------L 134
            ::.....|.|||::|.|.|.:....|.::...::..|:..|:...:....:.:|..:       .
Human   139 DVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLA 203

  Fly   135 EAAKDPAATTARSFKHVDSAETDDAATNSTTS------TTMTTSSAPPLPVNHQQPTVLKRQNPD 193
            :...||...||.  ||  .|:|..|...:|..      ..:|...:..:|.: |.||.......:
Human   204 DRHSDPELYTAA--KH--CAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCS-QNPTEAIEAWIN 263

  Fly   194 ARQQQQQQQQQQVQQRPQINGSNAQ-----QPSKATSTNVLGSHSNAPTEDDS 241
            ..:::::...:.::...:..|.|..     :.|..|.:..:..|.   .||||
Human   264 FNKEEREAFAESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHC---AEDDS 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8924	NP_573091.1	BTB_POZ_BAB-like	32..116	CDD:349624	25/84 (30%)
		MerR	378..407	CDD:425647
KBTBD4	NP_001305645.1	KELCH repeat	367..414	CDD:276965
		KELCH repeat	417..463	CDD:276965
		KELCH repeat	471..516	CDD:276965
		BTB_POZ_KBTBD4	62..201	CDD:349581	32/126 (25%)
		PHA03098	96..528	CDD:222983	49/226 (22%)
		BACK_KBTBD4	191..278	CDD:350556	16/91 (18%)
		KELCH repeat	328..363	CDD:276965