Protein Alignment CG8924 and ZBTB12

DIOPT Version :9

• Sequence 1: NP_573091.1
• Gene: CG8924 / 32557
• FlyBaseID: FBgn0030710
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_862825.1
• Gene: ZBTB12 / 221527
• HGNCID: 19066
• Length: 459
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 96/520 - (18%)
• Similarity: 151/520 - (29%)
• Gaps: 173/520 - (33%)

  Fly    25 QLLAGQRFVDVTLACEGQQVHCHRLVLAACSTYFEAILAEHPCKHPVIILPREIKLWEIQALVDF 89
            ||.|.:||.|||:..:..:...|:::|||||.:.......:|.....:.|....::  :..|:..
Human    25 QLRAEERFCDVTIVADSLKFRGHKVILAACSPFLRDQFLLNPSSELQVSLMHSARI--VADLLLS 87

  Fly    90 MYKGEVNVTQAGLGQLLRCAEQLQIRGLYGS---------EAPINYKK--LQQASLEAAKDPAAT 143
            .|.|.:......:...|..|..||:..:...         |..|..|:  :.:|||
Human    88 CYTGALEFAVRDIVNYLTAASYLQMEHVVEKCRNALSQFIEPKIGLKEDGVSEASL--------- 143

  Fly   144 TARSFKHVDSAETDDAATNSTTSTTMTTSSA------PPLPVNHQQPTVLKRQNPDARQQQQQQQ 202
                   |.|.    :||.|......|...|      ||||     |.:|:
Human   144 -------VSSI----SATKSLLPPARTPKPAPKPPPPPPLP-----PPLLR-------------- 178

  Fly   203 QQQVQQRPQINGSNAQQPSKATSTNVLGSHSNAPTEDDSGDEVPNNWNAYGEQFDDCNISAQA-- 265
                             |.|............|..||:..||         :..|.|.:..::
Human   179 -----------------PVKLEFPLDEDLELKAEEEDEDEDE---------DVSDICIVKVESAL 217

  Fly   266 -----------------VDNKMNVHLSLQQARMQMQLQQQQYLDSNVEDDHNYV-AAHDENNDSS 312
                             :...:..||.        :|.|.....|.|......| |.:..:.|:.
Human   218 EVAHRLKPPGGLGGGLGIGGSVGGHLG--------ELAQSSVPPSTVAPPQGVVKACYSLSEDAE 274

  Fly   313 FATGVPCGSGLSLSLDTDLDTSANTSGGLSHSSIDGYTSYKRVRRSEASLAQAA----------- 366
                   |.||.|.      .....|.|.:...::........|.:..||....
Human   275 -------GEGLLLI------PGGRASVGATSGLVEAAAVAMAARGAGGSLGAGGSRGPLPGGFSG 326

  Fly   367 -------KCVSKGETFQTVSNMFNIPVSTIRFYM-ARKGILPKRKRGRGASHAGNIIITTN---- 419
                   ||....|.||.|..:.        |:| |:..|....:.|:..:|:.|:....|
Human   327 GNPLKNIKCTKCPEVFQGVEKLV--------FHMRAQHFIFMCPRCGKQFNHSSNLNRHMNVHRG 383

  Fly   420 --------SGKLSTVPASITHPPAHPHIHTNPLPHTQS------QQMSMDSLHLKAGIANTSGSN 470
                    .||..|..::: |.  |.::|:...|:..|      ........|||.....|:..|
Human   384 VKSHSCGICGKCFTQKSTL-HD--HLNLHSGARPYRCSYCDVRFAHKPAIRRHLKEQHGKTTAEN 445

  Fly   471  470
            Human   446  445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8924	NP_573091.1	BTB	25..117	CDD:279045	23/91 (25%)
		BTB	34..117	CDD:197585	18/82 (22%)
		MerR	378..407	CDD:278788	6/29 (21%)
ZBTB12	NP_862825.1	BTB	23..127	CDD:306997	23/103 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..179		8/61 (13%)
		C2H2 Zn finger	335..355	CDD:275368	7/27 (26%)
		zf-C2H2	359..381	CDD:306579	4/21 (19%)
		COG5048	<361..>448	CDD:227381	17/88 (19%)
		C2H2 Zn finger	361..381	CDD:275368	4/19 (21%)
		C2H2 Zn finger	389..409	CDD:275368	5/22 (23%)
		C2H2 Zn finger	417..435	CDD:275368	2/17 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000