DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8924 and Bach2

DIOPT Version :9

Sequence 1:	NP_573091.1	Gene:	CG8924 / 32557	FlyBaseID:	FBgn0030710	Length:	514	Species:	Drosophila melanogaster
Sequence 2:	XP_006537629.1	Gene:	Bach2 / 12014	MGIID:	894679	Length:	846	Species:	Mus musculus

Alignment Length:	551	Identity:	117/551 - (21%)
Similarity:	194/551 - (35%)	Gaps:	151/551 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 DVTLACEGQQVHCHRLVLAACSTYFEAILAEHPCKHPVIILPREIKLWEIQALVDFMYKGEVNVT 98
            ||||..|.::...||.||||||.||...|........|:.||.|:.......|:.|.|..::.::
Mouse    45 DVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKDDLVVSLPEEVTARGFGPLLQFAYTAKLLLS 109

  Fly    99 QAGLGQLLRCAEQLQIRGLYGSEAPINYKKLQQASLE-----AAKDPAATTARSFKHVDSA---- 154
            :..:.:::||||.|::..|  .::..::.:.|..:.|     ..||.|....:. .|.:||
Mouse   110 RENIREVIRCAEFLRMHNL--EDSCFSFLQTQLLNREDGLFVCRKDSACQRPQE-DHGNSAGEEE 171

  Fly   155 ETDDAATNSTTSTTMTTSSAPPLPVNHQQPTVLKRQNPDARQQQQQQQQQQVQQRPQIN---GSN 216
            |.::...:.|......|....|.|::.:...:     |.|.:::....:.:|....:.|   |:.
Mouse   172 EEEETMDSETARMACATDQMLPDPISFEATAI-----PVAEKEEALLPESEVPTDTKENSEKGAL 231

  Fly   217 AQQP-----SKATSTNVLGSHSNAPTEDDSGDEVPNNWNAYGEQFDDCNISAQAVDNKMNVHLSL 276
            .|.|     ..|.:.||.    :||:...||         :...|.:        |:..|   ||
Mouse   232 TQYPRYKKYQLACTKNVY----SAPSHGTSG---------FASTFSE--------DSPGN---SL 272

  Fly   277 QQARMQMQLQQQQYLDSNVEDDHNYVAAHDENN-------------------DSSFATGVPCGSG 322
            :......|::.:...:...|:......:.||.:                   ..|..||..|
Mouse   273 KPGLPMGQIKSEPPSEETEEESITLCLSGDETDIKDRPGDVEMDRKQPSPAPTPSTPTGAAC--- 334

  Fly   323 LSLSLDTDLDTSANTSGGLSHSSIDGYTSYKRVR------RSEASLAQAAKC-----VSKGE--- 373
                    ||.|.:.|......|:.|.|  |.|.      .|:..|.:::.|     :|:|:
Mouse   335 --------LDRSRSVSSPSCLRSLFGIT--KGVESTGLPSTSQQPLVRSSACPFNKGISQGDLKT 389

  Fly   374 TFQTVSNMFNIPVSTIRFYMARKGI----LPKRKRGRGASHAGNIIITTNSGKLS----TVPASI 430
            .:..::..:..|      ::.:|.:    :....||.|..     .:....|:|.    ...||.
Mouse   390 DYTPLAGNYGQP------HVGQKDVSNFAMGSPLRGPGPE-----TLCKQEGELDRRSVIFSASA 443

  Fly   431 THPPAHPHIH------------TNPLPHT----------QSQQMSMDSL---HLKAGI-ANTS-- 467
            ...|..| :|            :.|:|.:          .||..|...|   ||...| .|||
Mouse   444 CDQPNTP-VHSYSAVSNLDKDLSEPVPKSLWVGAGQSLPSSQAYSHSGLMADHLPGRIRPNTSCP 507

  Fly   468 -----GSNSP--ATATATSMS-PSFDMATTG 490
                 ...||  .|.|.||.| .|:..|..|
Mouse   508 VPIKVCPRSPPLETRTRTSSSCSSYSYAEDG 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8924	NP_573091.1	BTB	25..117	CDD:279045	28/82 (34%)
		BTB	34..117	CDD:197585	28/82 (34%)
		MerR	378..407	CDD:278788	4/32 (13%)
Bach2	XP_006537629.1	BTB_POZ_BACH2	13..136	CDD:349587	29/92 (32%)
		bZIP_BACH	646..716	CDD:269867
		coiled coil	655..706	CDD:269867
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8160
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.950