Protein Alignment Stim and stim-1

DIOPT Version :10

• Sequence 1: NP_523357.2
• Gene: Stim / 32556
• FlyBaseID: FBgn0045073
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_741074.1
• Gene: stim-1 / 175201
• WormBaseID: WBGene00021910
• Length: 530
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 132/422 - (31%)
• Similarity: 209/422 - (49%)
• Gaps: 42/422 - (9%)

  Fly   138 VQDRFGMEAIASLHRQLDDDDNGNIDLSESDDFLREELKY-DSGYEKRQKAFHFNDDMHISVKEL 201
            ::|:.|.|||..:||.:|||.:|:||.:||..|::|:::. .|...:|:..||.:||. |:|.:|
 Worm    38 IRDKLGYEAIRDIHRDMDDDHSGSIDRNESTGFMKEDMQMRGSERTRRENKFHGDDDA-ITVDDL 101

  Fly   202 WEAWLRSEVHNWTIEQTTDWLAQSVQLPQYVDLFKLHKVTGAALPRLAVNNLQYVGNVLGIKDPI 266
            ||||..|....||.|:..:||...|.||..|:..|..|:.|..|||.|..|..::...||||..:
 Worm   102 WEAWFESIERTWTNERLVEWLINDVNLPSIVEAVKAKKIDGKILPRFASPNSDFLNKELGIKSSV 166

  Fly   267 HKQKISLKAMDVVLFGPPRETGTRWKDYIL--VTLLLSAIIGCWYAYQQNKNAKRHLRRMAQDME 329
            ::||:.|.::|||||| .::...|.||.:|  :.|||:::|   :.|.:.|
 Worm   167 YRQKLRLNSLDVVLFG-YKDNNNRTKDILLAFLALLLTSLI---FLYVRQK-------------- 213

  Fly   330 GLQRAEQSLQEMQKELERAR-MEQENVATEKLDLERRLKEAPTLSSSNSDLEVQQLKKEIEMLRN 393
              |:|:|.:.|:..:|...: ||.|....:|:..:.|.|.      |.||..|..  .|:|.||.
 Worm   214 --QKAQQKVNELSNKLTELKCMETEFEDVQKMLNDERSKR------SISDGVVNH--TEMENLRV 268

  Fly   394 ELSRAE--FELVDNCWSPPPQLQSWLQYTYELESKNHQKKRTSAEKQLQSAREACEKLRKKRSSL 456
            :|..||  .|...|....|..||..|:.|.|.|....:|:|....|:::.|.|..::|:||:.|:
 Worm   269 QLEEAERRLEANSNGSQAPLALQPLLRRTCENEMAFLEKQRQDCFKEMKEAIEMVDRLQKKQGSV 333

  Fly   457 VGAFVSTHG--KSIDDVDRSIVEARNALGDVTNELQERLHRWKQIETCLGLNIVNNNGLPYLENV 519
            :.:.....|  .:.|.||..|...::.:..:....:|...||.|||:..|..::..|...::...
 Worm   334 LSSLKLATGAASTSDQVDSKIFALKSRMEKIHTLTRETQERWLQIESLCGFPLLYLNETEHINRS 398

  Fly   520 L-----YGRNGGLQSSMGMSSTKGSRARITNS 546
            :     |.::....||.|..|...|.....||
 Worm   399 IASSHFYNKSHEGSSSSGSISNAHSNPNAVNS 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stim	NP_523357.2	SAM_STIM-1,2-like	209..282	CDD:188903	28/72 (39%)
		YhaN	312..>501	CDD:443752	51/193 (26%)
		SOAR	408..507	CDD:465164	28/100 (28%)
stim-1	NP_741074.1	SAM_superfamily	109..182	CDD:472832	28/72 (39%)
		SOAR	285..386	CDD:465164	28/100 (28%)