Protein Alignment Stim and Stim2

DIOPT Version :10

• Sequence 1: NP_523357.2
• Gene: Stim / 32556
• FlyBaseID: FBgn0045073
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: XP_038947488.1
• Gene: Stim2 / 117087
• RGDID: 1304641
• Length: 817
• Species: Rattus norvegicus
• Alignment Length: 475
• Identity: 188/475 - (39%)
• Similarity: 278/475 - (58%)
• Gaps: 44/475 - (9%)

  Fly   116 SMGSGSADGACAADDFD------CYSGS-----VQDRFGMEAIASLHRQLDDDDNGNIDLSESDD 169
            |.|:.::..|.||.:..      |.|.|     .:|||.:||:.::|:|:|||.:|.|::.|||:
  Rat    96 SAGAAASPSAAAAGERQALLTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVDESDE 160

  Fly   170 FLREELKYDSGYEKRQKAFHFN-DDMHISVKELWEAWLRSEVHNWTIEQTTDWLAQSVQLPQYVD 233
            |:||::||.....|..   |.: :|.||:|::||:.|..|||||||:|.|..||.:.|:||||..
  Rat   161 FIREDMKYKDATNKHS---HLHREDKHITVEDLWKQWKTSEVHNWTLEDTLQWLIEFVELPQYEK 222

  Fly   234 LFKLHKVTGAALPRLAVNNLQYVGNVLGIKDPIHKQKISLKAMDVVLFGPPRETGTRW-KDYILV 297
            .|:.:.|.|..|||:||:...::.:.|.|.|..|:||:.|||:|||||||.......| ||:||.
  Rat   223 NFRDNNVKGTTLPRIAVHETSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILT 287

  Fly   298 TLLLSAIIGCWYAYQQNKNAKRHLRRMAQDMEGLQRAEQSLQEMQKELERARMEQENVATEKLDL 362
            ..::..:.|||:||.|||.:|.|:.:|.:|:|.||.|||||.::|:.||:|:.|...||.||.:|
  Rat   288 ISIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRTVAVEKQNL 352

  Fly   363 ERRL--------KEAPTLSSSNSDLEV-----QQLKKEIEMLRNELSRA--EFELVDNCWSPPPQ 412
            ||::        :||..|.......|.     |..::|:|.:|..|.:|  |||| .:.||.|..
  Rat   353 ERKMMDEINYAKEEACRLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFEL-RSSWSVPDA 416

  Fly   413 LQSWLQYTYELESKNHQKKRTSAEKQLQSARE--------ACEKLRKKRSSLVGAFVSTHGKSID 469
            ||.|||.|:|:|.:.:..||.:||.||..|::        ..||::||||::.|.....|..|:|
  Rat   417 LQKWLQLTHEVEVQYYNIKRQNAEMQLAIAKDEVAASYLMQAEKIKKKRSTVFGTLHVAHSSSLD 481

  Fly   470 DVDRSIVEARNALGDVTNELQERLHRWKQIETCLGLNIVNNNGLPYLENVLYGRNGGLQSSMGMS 534
            :||..|:||:.||.::|..|:|||.||:|||...|..|.:|:|||.|.:.||..:    |.:.|.
  Rat   482 EVDHKILEAKKALSELTTCLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDH----SWVVMP 542

  Fly   535 STKGSRARITNSTEDLDDES 554
            ........|....:|||:::
  Rat   543 RVSIPPYPIAGGVDDLDEDT 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stim	NP_523357.2	SAM_STIM-1,2-like	209..282	CDD:188903	36/72 (50%)
		YhaN	312..>501	CDD:443752	85/211 (40%)
		SOAR	408..507	CDD:465164	45/106 (42%)
Stim2	XP_038947488.1	SAM_STIM2	198..271	CDD:188973	36/72 (50%)
		PRK00409	<316..496	CDD:234750	70/180 (39%)
		SOAR	412..519	CDD:465164	45/106 (42%)