DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stim and LOC101730384

DIOPT Version :9

Sequence 1:	NP_523357.2	Gene:	Stim / 32556	FlyBaseID:	FBgn0045073	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	XP_031760469.1	Gene:	LOC101730384 / 101730384	-ID:	-	Length:	568	Species:	Xenopus tropicalis

Alignment Length:	318	Identity:	141/318 - (44%)
Similarity:	200/318 - (62%)	Gaps:	17/318 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 SEVHNWTIEQTTDWLAQSVQLPQYVDLFKLHKVTGAALPRLAVNNLQYVGNVLGIKDPIHKQKIS 272
            |||||||.|:|..||.:.|:||||...|:.:.|.|.||||:|||....:.:.|.|.|..|:||..
Frog     4 SEVHNWTEEETLQWLLEFVELPQYEKNFRENSVKGTALPRIAVNEPVLMISQLKITDRSHRQKFQ 68

  Fly   273 LKAMDVVLFGPPRETGTRW-KDYILVTLLLSAIIGCWYAYQQNKNAKRHLRRMAQDMEGLQRAEQ 336
            |||:||||||||......| ||:||...::..:.|||:||.||:.:|.|:.:|.:|:||||:||.
Frog    69 LKALDVVLFGPPTRPPHNWVKDFILTISIVIGVGGCWFAYSQNRTSKEHISQMMKDLEGLQKAEI 133

  Fly   337 SLQEMQKELERARMEQENVATEKLDLERRL--------KEAPTLSS--SNSDLEVQQLK---KEI 388
            ||.|:|..||:|:.|...||.||.:|||::        :||..|..  ..::.|:.:||   :|:
Frog   134 SLLELQDRLEKAQEENRTVAVEKQNLERKMMDEISDAKREAHRLRELREGTECELSRLKYAEEEL 198

  Fly   389 EMLRNELSRA--EFELVDNCWSPPPQLQSWLQYTYELESKNHQKKRTSAEKQLQSAREACEKLRK 451
            ..:|..|.:|  ||||..| ||.|..||.|||.|:|:|.:.:..|:.:||..|..|::..||::|
Frog   199 VQVRMALKKAEKEFELRSN-WSVPETLQKWLQLTHEVEVQYYNIKKQNAEMHLAIAKDEAEKIKK 262

  Fly   452 KRSSLVGAFVSTHGKSIDDVDRSIVEARNALGDVTNELQERLHRWKQIETCLGLNIVN 509
            |||::.|.....|..|:|:||..|:||:.||.::|..|:|||:||:|||...|..||:
Frog   263 KRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLYRWQQIEKMCGFPIVH 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stim	NP_523357.2	SAM_STIM-1,2-like	209..282	CDD:188903	38/72 (53%)
		SAM	210..271	CDD:197735	29/60 (48%)
		GBP_C	<312..392	CDD:303769	34/92 (37%)
		coiled coil	360..372	CDD:293879	5/19 (26%)
		coiled coil	381..392	CDD:293879	3/13 (23%)
		SOAR	410..507	CDD:293141	42/96 (44%)
LOC101730384	XP_031760469.1	SAM_STIM2	5..78	CDD:188973	38/72 (53%)
		PRK00409	<128..242	CDD:234750	45/114 (39%)
		SOAR	221..318	CDD:406837	42/96 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	109	1.000	Domainoid score	I6270
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001884
OrthoInspector	1	1.000	-	-		otm49137
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1416
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.910