Protein Alignment Lcch3 and gabra5

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_005166139.1
• Gene: gabra5 / 799124
• ZFINID: ZDB-GENE-081104-30
• Length: 453
• Species: Danio rerio
• Alignment Length: 506
• Identity: 159/506 - (31%)
• Similarity: 239/506 - (47%)
• Gaps: 102/506 - (20%)

  Fly    12 GLFFFLLGAQLQLIRCI----RKDVLAGRLENVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTI 72
            |:.|..|...|.|.:..    ::..|...:...|:.:..:|.|||.||||..|.:...:..::.:
Zfish    17 GVLFMTLTCHLSLSQSTTGTPKESELNDNITVFTRILDGLLDGYDNRLRPGLGEKVTEIKTNIFV 81

  Fly    73 ASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTF 137
            .||..:|:..|:|||.::..|.|:||||.|.            |..::|.|:...|..||.||||
Zfish    82 TSFGPVSDTEMEYTIDVFFRQSWKDERLCFK------------GPMEMLPLNNLLASNIWTPDTF 134

  Fly   138 FANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVS 202
            |.|.|.|..|::|..|||:||..||.:.|.||.|.:..|.|.|..:|:|:..|.::..||.|.:|
Zfish   135 FLNGKKSIAHNMTTPNKLLRLKDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPIS 199

  Fly   203 DVVMYWKPTPVRGV----EDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQT 263
            :||..|...|.:.|    |.:.|.|:.:||:.........:.|.|..:...|.|:|.|||||.||
Zfish   200 EVVYKWTKGPGKSVVVAEEGSRLNQYHLIGHTAGTEDISTSRGQYTVMMAHFYLKRKIGYFVIQT 264

  Fly   264 YLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFV 328
            |:|..:.|:||.||||:|.|:..||...|:||||||||:|...|:|||:::|..|:|.::.:|:.
Zfish   265 YMPCFMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYA 329

  Fly   329 FVFAALLEYAAVNY---TYWGKRAKKKI--KKVKECCPGKIGKSERSETCSTTED---------- 378
            |||:||:|:|.|||   ..|....||.:  ::.|:..|..:.|...:.|.:..:|
Zfish   330 FVFSALIEFATVNYFTKRSWAWDGKKALEAQQPKKKDPLALSKKPNNFTANINKDAAISTISNST 394

  Fly   379 IIELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTR 443
            .::|:.....|.|..:: |||:
Zfish   395 TVQLKSAEAKPAPDPKK-TYNS------------------------------------------- 415

  Fly   444 PRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYWLFYI 494
                                   |:.|||.||::||:.|..|||.||..|:
Zfish   416 -----------------------VSKIDKMSRIVFPVLFGTFNLVYWATYL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	157/500 (31%)
		Neur_chan_LBD	47..256	CDD:280998	75/212 (35%)
		Neur_chan_memb	263..490	CDD:280999	68/241 (28%)
gabra5	XP_005166139.1	Neur_chan_LBD	19..442	CDD:332142	157/501 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900