Protein Alignment Lcch3 and glrb

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001072255.1
• Gene: glrb / 779708
• XenbaseID: XB-GENE-1011734
• Length: 497
• Species: Xenopus tropicalis
• Alignment Length: 495
• Identity: 173/495 - (34%)
• Similarity: 252/495 - (50%)
• Gaps: 90/495 - (18%)

  Fly    39 NVTQTISN-ILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAF 102
            |.|..|.| :|..||.|:||||.|.|:.|.:::.|.||.:|.|..|||.:.::|.|.|.|.||..
 Frog    54 NSTSNILNRLLVSYDPRVRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLKL 118

  Fly   103 NIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYG 167
                     .||...||.||:.....:.:|.||.||||:||:..||||:.|.|:.:..||.|...
 Frog   119 ---------PNDFRGSDALTVDPTMFKCLWKPDLFFANEKNANFHDVTQENILLFIFRDGDVLLS 174

  Fly   168 MRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKP-TPVRGVEDAELPQFTI----I 227
            ||.:.||:|.:||..:|:|:|.|.:::||:|||..|:...|:. .||: :|...||||.|    |
 Frog   175 MRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQ-MEKIALPQFDIKTEDI 238

  Fly   228 GYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALG 292
            .| .|..|....||.|..:.:.|.|:|.:|:::...|.|::|||:|||:|||||.:|::|||.||
 Frog   239 EY-GNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLG 302

  Fly   293 ITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVK 357
            |.:||::.:..|.:...||::|||||||::|:.|.:|.||:|:|||.|....   .:.|:|:..|
 Frog   303 IFSVLSLASECTTLAQELPKVSYVKAIDVWLIACLLFGFASLVEYAVVQVLL---NSPKRIEAEK 364

  Fly   358 ECCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGK-------- 414
                .||.|:|::|.....               :.::.|.|.|...|...|:.:|:
 Frog   365 ----AKIAKAEQAEGKGAN---------------AAKKNTVNGTGTPIHISTLQVGENRCKKVCT 410

  Fly   415 ---------------FPPSFRITR----------NYGTGHSQLRRRAQRGISTRPRMLHALKRGA 454
                           .|..|.::.          |.|.|.||.:..               |:..
 Frog   411 SKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNN---------------KKPP 460

  Fly   455 SAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYWLFYI 494
            .| |..||  .:...||.|||.:||..||.||:.|||.|:
 Frog   461 PA-KPVIP--SEAKRIDLYSRALFPFCFLFFNVIYWLVYL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	172/492 (35%)
		Neur_chan_LBD	47..256	CDD:280998	85/213 (40%)
		Neur_chan_memb	263..490	CDD:280999	79/259 (31%)
glrb	NP_001072255.1	LIC	38..496	CDD:273305	172/492 (35%)
		LGIC_ECD_GlyR_beta	79..265	CDD:349811	75/196 (38%)
		Cys-loop	183..197	CDD:349811	6/13 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910