Protein Alignment Lcch3 and gabrr2b

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_697486.2
• Gene: gabrr2b / 569032
• ZFINID: ZDB-GENE-041014-174
• Length: 464
• Species: Danio rerio
• Alignment Length: 476
• Identity: 188/476 - (39%)
• Similarity: 256/476 - (53%)
• Gaps: 101/476 - (21%)

  Fly    48 LQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDE 112
            ::.:|..:||.|.|..:.||:|:.:.|.|:||||:||:|:|:||..||:||||:|.      ...
Zfish    61 VEDHDFTMRPAFAGPAVPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFP------SKH 119

  Fly   113 NDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACM 177
            |..     :|..|...:||||||.||.:.|.||:||.|..|.::|:..||.|.|.:|.|.|.||.
Zfish   120 NKS-----MTFDGRLVKKIWVPDVFFVHSKRSFIHDTTTENIMIRVYPDGHVLYSLRVTVTSACN 179

  Fly   178 MDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGVED------AELPQFTIIGYETNDRKE 236
            ||...:|||:|.||:|:|||.||..|:::|||    .|.|.      ..|.||.|..:.|.   .
Zfish   180 MDFSRFPLDTQTCTLELESYAYTDEDLMLYWK----SGDESLSTDDKISLSQFLIQKFHTT---S 237

  Fly   237 RLA----TGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVL 297
            |||    ||.|.||.::|.|:|:|.:|:.|||.|:.|:||||||||||:..|..|||:|||||||
Zfish   238 RLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVL 302

  Fly   298 TMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNY---TYWGKRAKKKIKKVKEC 359
            ||:||.|||.:|:||:||:||:||||.:.|||||.::||||||||   .:.|...|.:.|.:...
Zfish   303 TMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVHDGTDRKLRQKTLPGT 367

  Fly   360 C----------------PGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTE 408
            |                |...|.:..::|..::|:..|.||    ||         |...|||.|
Zfish   368 CDISSMRTMMLNEAYGRPDSNGLAGYTQTTVSSEEPAEKQD----PI---------AVCLSIGPE 419

  Fly   409 TMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKY 473
            ...                    .::|..||:..                     |::.:.||.|
Zfish   420 VKG--------------------AKKRTLRGLRI---------------------IQNTHAIDAY 443

  Fly   474 SRMIFPISFLAFNLGYWLFYI 494
            ||||||.:|:.|||.||..|:
Zfish   444 SRMIFPGAFIFFNLIYWSVYL 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	187/473 (40%)
		Neur_chan_LBD	47..256	CDD:280998	91/217 (42%)
		Neur_chan_memb	263..490	CDD:280999	91/245 (37%)
gabrr2b	XP_697486.2	LIC	55..463	CDD:273305	187/473 (40%)
		Neur_chan_LBD	56..261	CDD:280998	91/217 (42%)
		Neur_chan_memb	268..460	CDD:280999	91/245 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910