Protein Alignment Lcch3 and gabrz

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001108214.2
• Gene: gabrz / 561738
• ZFINID: ZDB-GENE-080303-26
• Length: 447
• Species: Danio rerio
• Alignment Length: 502
• Identity: 189/502 - (37%)
• Similarity: 271/502 - (53%)
• Gaps: 78/502 - (15%)

  Fly    11 CGLFFFLLGAQLQLIRCIRKDVLAGRLENVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASF 75
            |....|||  .|..|..|....:|...|.:..||..:::||:..|||.||..|:.|||.|.|||.
Zfish     4 CSFVGFLL--LLLFISRIMDGSVANTEEILPPTIQKLMKGYNKYLRPFFGNGPVTVGMSLDIASI 66

  Fly    76 DAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFAN 140
            |.|||:|||||.|::|.|.|.||||.|            || :..|:|.|...|.:||||||..:
Zfish    67 DTISEINMDYTATIFLRQRWTDERLCF------------DG-NKSLSLDGRLVELLWVPDTFIVD 118

  Fly   141 DKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVV 205
            .|.|||||:|..|:|:|:..:|.|.|.:|.|||:||.|||..||:|.|.|.:::||:||.|.|||
Zfish   119 SKKSFLHDITVENRLIRIFPNGTVLYALRITTTVACSMDLTKYPMDRQTCMLQLESWGYNVKDVV 183

  Fly   206 MYWK--PTPVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSI 268
            .||.  ...|.|::..:|.|:|:..:.|::.:....||.|.:|...|||:|:|.||:.:||:||.
Zfish   184 FYWTRGNQSVSGLDHLQLAQYTLEDHYTSESEAVYETGNYPKLIFHFKLKRSILYFILETYVPSS 248

  Fly   269 LIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRIS-YVKAIDIYLVMCFVFVFA 332
            .:|:||||||||:..:..||:.:|:||||||||:..|.|:|||..: ::||||:||.:||.|:|.
Zfish   249 ALVVLSWVSFWISQSSVPARICIGVTTVLTMTTLMMGARTSLPNANCFIKAIDVYLGICFSFIFG 313

  Fly   333 ALLEYA-----------AVNYTYWGKRAKKKIKKVKECCPG----KIGKSERSETCSTTEDIIEL 382
            ||:|||           |.|...:|:..:::..::......    .:...:|.|..|
Zfish   314 ALIEYAVAHFCTLHQPNAANAYMYGQEMQEREDEMNGIVTSFGSHALRARKREEMLS-------- 370

  Fly   383 QDVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRML 447
                       |.|:.|....|...|.::..:  |..|.|:        ...||:|.|    |.|
Zfish   371 -----------RMGSVNNPTPSESKEDVSSSQ--PQTRCTK--------CMSRARRII----RCL 410

  Fly   448 HALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYWLFYI 494
            :..            |:::.:.||.|||:.||:||:..||.||.:|:
Zfish   411 YCC------------KVENPHYIDNYSRLTFPLSFVIINLLYWTYYL 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	187/495 (38%)
gabrz	NP_001108214.2	LIC	26..444	CDD:455710	180/475 (38%)
		LGIC_ECD_GABAAR_pi	54..235	CDD:349805	88/193 (46%)
		Cys-loop	153..168	CDD:349805	9/14 (64%)