Protein Alignment Lcch3 and gabra6b

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_002667403.3
• Gene: gabra6b / 559693
• ZFINID: ZDB-GENE-080815-1
• Length: 444
• Species: Danio rerio
• Alignment Length: 464
• Identity: 168/464 - (36%)
• Similarity: 249/464 - (53%)
• Gaps: 63/464 - (13%)

  Fly    37 LENVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLA 101
            |:|:|:.:..:|.|||.||||.|||....|..|:.:.||..:|:|.|:||:.::..|.|.|:||.
Zfish    28 LDNITRILDRLLDGYDNRLRPGFGGPVTEVKTDIFVTSFGPVSDVEMEYTMDVFFRQTWIDDRLK 92

  Fly   102 FNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTY 166
            |            :|..::|.|:.....|||.|||||.|.|.|..|::|..|||.|:..:|.:.|
Zfish    93 F------------EGPIEILRLNNLMVSKIWTPDTFFRNGKRSISHNMTTPNKLFRIMQNGTILY 145

  Fly   167 GMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGV----EDAELPQFTII 227
            .||.|....|.|.|..:|:|..:|.::..||.|.:|::|..||..|:..|    |.:.|.|:.:|
Zfish   146 TMRLTINAECPMRLINFPMDGHSCPLKFGSYAYPMSEIVYTWKKGPLFSVEVPQESSSLLQYDLI 210

  Fly   228 GYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALG 292
            |...:..:.:..||.|..:::.|.|||.:|:|:.|||:|.|:.|:|:.|||||:.|:..||...|
Zfish   211 GQTVSSERLKSNTGEYIVMTVYFHLQRKMGFFLIQTYIPCIMTVILAQVSFWIDKESVPARTVFG 275

  Fly   293 ITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVK 357
            |||||||||:|...|.|||::||..|:|.::.:||.|||:||:|:||||| :...:|.|::::..
Zfish   276 ITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNY-FSTLQANKELRRAN 339

  Fly   358 ECCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGT--ETMNLGKFPPSFR 420
            .........:.||:                      ..|..| .||..|.  :.||
Zfish   340 IARAAAAAAAARSD----------------------GEGVLN-PLDPGGVLKKRMN--------- 372

  Fly   421 ITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAF 485
                      .|.:|:.....:||......::| ||:.|....| ..:|||||||::||:||.||
Zfish   373 ----------SLSQRSATDRFSRPSQSDFHQQG-SAVPANNMLI-GTSIIDKYSRILFPLSFGAF 425

  Fly   486 NLGYWLFYI 494
            ||.||:.|:
Zfish   426 NLVYWIVYL 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	167/461 (36%)
gabra6b	XP_002667403.3	LIC	33..433	CDD:455710	164/456 (36%)
		LGIC_ECD_GABAAR_A6	41..238	CDD:349840	76/208 (37%)
		Cys-loop	155..169	CDD:349840	5/13 (38%)