Protein Alignment Lcch3 and Grd

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 595
• Identity: 181/595 - (30%)
• Similarity: 267/595 - (44%)
• Gaps: 170/595 - (28%)

  Fly    39 NVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFN 103
            |:::.:.|:|:|||..:||:|||.|..:.:|:.:.|...||||:|.|::..|..|.|.|:||||
  Fly   108 NISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAF- 171

  Fly   104 IFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGM 168
                       :|..|.|.||.....:||.|||:|.|.|.|:||.:|..||.||:..:|.|.|..
  Fly   172 -----------EGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSS 225

  Fly   169 RFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYW---KPTPVRGVEDAELPQFTII--- 227
            |.|....|.|:|..:|:|.|.|.::..|:|||.|||:..|   :| ||...||.:|.||.::
  Fly   226 RLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERP-PVAIAEDMKLSQFDLVDCP 289

  Fly   228 -GYETN---------------DRKE-------------------------------------RLA 239
             |..|:               :.|:                                     |.|
  Fly   290 AGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDA 354

  Fly   240 TG--------------------VYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEA 284
            ||                    .|..|.::|.|||::|.|:.|.|.|..|:|:|||||||:|.||
  Fly   355 TGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREA 419

  Fly   285 TSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRA 349
            |:.||:||||||||||.:....|:.||::||..|:|.::.:.|.|:||.:|::|.|:  |:.|..
  Fly   420 TADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVH--YYTKYG 482

  Fly   350 KKKIKKVKECCPGKIGKSE--------RSETCSTTEDIIELQ--DVRMSPIP------------- 391
            ..:...:.|....:.|:||        |..|.|...::|.|.  .:.|.|.|
  Fly   483 SGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRP 547

  Fly   392 -SLRRGTYNATLDSIGTETMNLGKF-------PPSFRITRNYGTGHSQLRRRAQRGIST------ 442
             :.|.|.::..|         ||.|       ||  |...:......|.:.||....:|
  Fly   548 RNRRHGLWSMKL---------LGLFDWRRRRKPP--RADSDEDEDDEQTQLRANEAPTTSAAAAA 601

  Fly   443 ----------------RPRM-------LHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLA 484
                            |.||       :.|.::|    |.| |:...|:.||:.||::||:.|:.
  Fly   602 AQAAAQAARISPPTGGRRRMSYYRREEMEARRKG----KRT-PQYNSVSKIDRASRIVFPLLFIL 661

  Fly   485 FNLGYWLFYI 494
            .|:.||..|:
  Fly   662 INVFYWYGYL 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	180/592 (30%)
		Neur_chan_LBD	47..256	CDD:280998	88/287 (31%)
		Neur_chan_memb	263..490	CDD:280999	85/286 (30%)
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	79/228 (35%)
		LIC	111..670	CDD:273305	179/589 (30%)
		Neur_chan_memb	398..667	CDD:280999	85/286 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447355
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840