DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lcch3 and gabra6a

DIOPT Version :9

Sequence 1:NP_996469.1 Gene:Lcch3 / 32554 FlyBaseID:FBgn0010240 Length:496 Species:Drosophila melanogaster
Sequence 2:XP_005173169.1 Gene:gabra6a / 393704 ZFINID:ZDB-GENE-040426-1692 Length:435 Species:Danio rerio


Alignment Length:470 Identity:168/470 - (35%)
Similarity:239/470 - (50%) Gaps:84/470 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 ENVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAF 102
            ||:|:.:..:|:|||.||||..|.....|..|:.:.||..:|:|||::|:.|:..|.|.||||||
Zfish    25 ENITRILDGLLEGYDNRLRPGSGVSVTEVKTDIFVTSFGPVSDVNMEFTMDMFFRQMWVDERLAF 89

  Fly   103 NIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYG 167
                        .|..::|.|:....:|||.|||||.|.:.|..|::|..|||.|:..:|.|.|.
Zfish    90 ------------QGPIEILPLNNRMVDKIWTPDTFFRNARKSLAHNMTSPNKLFRIMQNGTVFYT 142

  Fly   168 MRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGV--------EDAELPQF 224
            ||.|.:..|.|.|..:|:|...|.:...||.||..::|..|:    :|:        |.:.|.|:
Zfish   143 MRLTVSAVCPMVLRDFPMDGHTCPLYFGSYAYTNREIVYTWR----KGLEASVDFPPESSSLLQY 203

  Fly   225 TIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARV 289
            .::|........:.:||:|....:.|.|||.:||.:.|||:|.|::|:||.||||||.|:..||.
Zfish   204 DLLGQTLFTETYKFSTGLYSVQVVHFYLQRKLGYHLIQTYIPLIMVVVLSQVSFWINKESVPART 268

  Fly   290 ALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNY--TYWGKRAKKK 352
            ..||||||||||:|...|||||::||..|:|.::.:||.||.:||:|:|||||  |....|...|
Zfish   269 VAGITTVLTMTTLSISARSSLPKVSYATAMDWFIAVCFAFVASALVEFAAVNYYATLEANRENHK 333

  Fly   353 IKKVKECCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPP 417
            :.:      |.|.:|:    ...::|..|......|.....|||                  :|.
Zfish   334 LPR------GSIVESQ----AQGSDDEPESPQSDTSAYSRKRRG------------------YPV 370

  Fly   418 SFRITRNYGTGHSQLRRRAQ---RGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFP 479
            |           ...|.|..   :|.:..|.|:.|   |.||             ||||||::||
Zfish   371 S-----------EAPRTRVPIFLQGSAFPPNMMLA---GTSA-------------IDKYSRILFP 408

  Fly   480 ISFLAFNLGYWLFYI 494
            ::|..|||.||..|:
Zfish   409 LAFGIFNLVYWYIYL 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lcch3NP_996469.1 LIC 15..493 CDD:273305 167/467 (36%)
Neur_chan_LBD 47..256 CDD:280998 76/216 (35%)
Neur_chan_memb 263..490 CDD:280999 83/231 (36%)
gabra6aXP_005173169.1 LIC 2..422 CDD:273305 167/467 (36%)
Neur_chan_LBD 28..234 CDD:280998 76/221 (34%)
Neur_chan_memb 242..419 CDD:280999 83/231 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3644
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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