Protein Alignment Lcch3 and lgc-36

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001023766.1
• Gene: lgc-36 / 3565335
• WormBaseID: WBGene00008551
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 144/530 - (27%)
• Similarity: 234/530 - (44%)
• Gaps: 135/530 - (25%)

  Fly    35 GRLENVTQTISNILQGYDIRLRPNF-GGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDE 98
            |..:|||..::|:|:.||...||.| .|:|..|.:||.|.:...:|::...|:...|..|.|.|:
 Worm    57 GVAQNVTHLLNNVLKNYDQHFRPGFNSGKPTKVYIDLFIRTMGPVSDLFNTYSFNCYFRQKWTDD 121

  Fly    99 RLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGA 163
            ||.||..|..|..         |:||....:|||.|||:|.|...|::|.:|..|:||||..||.
 Worm   122 RLHFNNSGIGFRQ---------LSLSMAMLDKIWKPDTYFWNGAGSYVHGITTSNRLVRLEPDGT 177

  Fly   164 VTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGVED---------A 219
            :.|..|.|....|.||:..||||.|.|.:.|.||.|:..:|...|:   :.|.::         |
 Worm   178 ILYSSRITVKAKCQMDMSRYPLDKQACRLVIGSYAYSSDEVQYKWR---IMGDDNGVKIDYESIA 239

  Fly   220 ELPQFTIIGYE-------TNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVS 277
            :||||::.|::       |.|::       |..|.:.|...|:.|||:...|:|..|:|:|.||:
 Worm   240 DLPQFSLSGFKVYKPANITRDKE-------YSALEVRFYFDRHFGYFLMNFYVPCALVVLLCWVA 297

  Fly   278 FWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNY 342
            |:...|||:.|:.:|||.|||:..||...:|..|::....|:::::.:|::.....::|:..|:|
 Worm   298 FFTKREATAERIGIGITNVLTIVLISMDSKSDSPKVDSPTALEVFIWICYLTHLICMVEFTVVHY 362

  Fly   343 -TYWG-----------KRAKKKIKKVKE----------------CCPGKIG-------------- 365
             |.:.           :|.::.||::.:                ..|..|.
 Worm   363 HTKYNTGDPEIQEVERERLRQIIKQIPKNTNNRATEPTFRRRNAALPVSIARPLPNKTKRFMSVR 427

  Fly   366 ---KSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETM---NLGKFPPSFRITRN 424
               |||::|:       |:|    |..|.::...|:|....|:..|::   |:|.....:.|..|
 Worm   428 QPKKSEQTES-------IQL----MRKISNMESTTHNEVESSLNLESIRQENVGWRLYYWMIDHN 481

  Fly   425 -----YGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLA 484
                 :|...:...|                                   |||.|.::.|:.|:.
 Worm   482 IKTDPFGVAQNSTSR-----------------------------------IDKISVIVAPLIFIL 511

  Fly   485 FNLGYWLFYI 494
            ....|:.||:
 Worm   512 TIALYYDFYV 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	142/527 (27%)
lgc-36	NP_001023766.1	LIC	48..520	CDD:455710	142/527 (27%)
		LGIC_ECD_GABAR_GRD-like	86..275	CDD:349808	68/207 (33%)
		Cys-loop	190..204	CDD:349808	8/13 (62%)