DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lcch3 and srsx-31

DIOPT Version :9

Sequence 1:NP_996469.1 Gene:Lcch3 / 32554 FlyBaseID:FBgn0010240 Length:496 Species:Drosophila melanogaster
Sequence 2:NP_001023767.1 Gene:srsx-31 / 3565162 WormBaseID:WBGene00008552 Length:308 Species:Caenorhabditis elegans


Alignment Length:265 Identity:48/265 - (18%)
Similarity:89/265 - (33%) Gaps:100/265 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 ISDVLTLSGDFAEKIWVPDTFFANDKNS-------FLHDV----TERNKLVRLGGD--------- 161
            ::|:..:||.|....    ..|.:||:|       .:|.|    .....|:.:|.|         
 Worm    52 LADLFHVSGHFVFNY----QLFNDDKSSQAACFFMMIHTVIGYCISGPLLLAIGIDRIIACRFPI 112

  Fly   162 --------GAVTYGMR--FTTTLACMMDLHYYPLDSQN----CTVEI----ESYGY--------T 200
                    |:|..|::  |..|....:.::.|.....|    |...:    :::||        .
 Worm   113 TYRLLLSYGSVYLGIQLIFPITFTSALMIYGYQFIDYNTQIICMAPLALPRQAFGYFTYSSNIIN 177

  Fly   201 VSDVVMYWKPTPVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYL 265
            |..|::|            ....|.:.||     |||.|               |...:||::..
 Worm   178 VKIVIVY------------AYTYFVLRGY-----KERDA---------------NRMRYVFKSIA 210

  Fly   266 PSILIVMLSWVSFWINH-------------EATSARVALGIT-----TVLTMTTISTGVRSSLPR 312
            .::::|::.|.:..|.:             |..|.....|:.     .|:....|::..||::.|
 Worm   211 LTVIVVLIGWTTVTIGNTIALGVIEDRHTSEIISIHAGFGVNISCSINVIVFYAINSEYRSAIRR 275

  Fly   313 ISYVK 317
            :..:|
 Worm   276 LFGMK 280

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lcch3NP_996469.1 LIC 15..493 CDD:273305 48/265 (18%)
Neur_chan_LBD 47..256 CDD:280998 33/184 (18%)
Neur_chan_memb 263..490 CDD:280999 12/73 (16%)
srsx-31NP_001023767.1 TM helix 1 11..36 CDD:341315
7TM_GPCR_Srsx 19..277 CDD:255903 47/260 (18%)
TM helix 2 43..67 CDD:341315 4/18 (22%)
TM helix 3 79..109 CDD:341315 5/29 (17%)
TM helix 4 122..140 CDD:341315 4/17 (24%)
TM helix 5 165..190 CDD:341315 5/36 (14%)
TM helix 6 201..230 CDD:341315 5/28 (18%)
TM helix 7 241..266 CDD:341315 4/24 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3644
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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