Protein Alignment Lcch3 and gabrb2a

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001019558.2
• Gene: gabrb2a / 336252
• ZFINID: ZDB-GENE-030131-8196
• Length: 519
• Species: Danio rerio
• Alignment Length: 532
• Identity: 236/532 - (44%)
• Similarity: 312/532 - (58%)
• Gaps: 77/532 - (14%)

  Fly    16 FLLGAQLQLIRCIRKDVLAGRLENVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISE 80
            |||...:..:.|.:.......:..|..|:..:::||||||||:|||.|:.|||::.|||.|.:||
Zfish    11 FLLCPLIVAVACAQSIRDPSNMPVVKDTVDRLMKGYDIRLRPDFGGAPVAVGMNIDIASIDMVSE 75

  Fly    81 VNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDV---LTLSGDFAEKIWVPDTFFANDK 142
            ||||||:|||..|.|||:||::               |::   |||....|:::|||||:|.|||
Zfish    76 VNMDYTLTMYFQQAWRDKRLSY---------------SEIPLNLTLDNRVADQLWVPDTYFLNDK 125

  Fly   143 NSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMY 207
            .||:|.||.:|:::||..||.|.||:|.|||.||||||..||||.||||:||||||||..|:..|
Zfish   126 KSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFY 190

  Fly   208 WK--PTPVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILI 270
            |:  ...|.|||..|||||:|:.|:...:....:||.|.||||||||:||||||:.|||:|||||
Zfish   191 WRGGDGAVSGVERIELPQFSIVDYKLISKNVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 255

  Fly   271 VMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALL 335
            .:|||||||||::|::||||||||||||||||:|.:|.:||:|.||||||:||:.||||||.|||
Zfish   256 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALL 320

  Fly   336 EYAAVNYTYWGKRAKKKIKKVKECCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNA 400
            |||.|||.::|:..:::.|..::.......|............:::..|...:.:.......|::
Zfish   321 EYAFVNYIFFGRGPQRQKKAAEKAATANNEKLRPDPNKWLVGSVVQRDDALYARMKQREIDGYDS 385

  Fly   401 TLDSIGTETMNLG-------KFPPSFRIT------------------------------------ 422
            ..|.|..|...||       ..|...|:|
Zfish   386 MWDPIFAEDAALGLGDQRLKMTPDDIRLTTVEMKNEMGPSDLSRGLGDPRSTMLAYDSSTLQYRR 450

  Fly   423 -----RNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISF 482
                 :||  |||.|.|.|.:..|       .|:|.||.:|..||.:.|||.|||:||||||..|
Zfish   451 AAMARQNY--GHSALERHATQKKS-------RLRRRASQLKVNIPDLSDVNSIDKWSRMIFPTLF 506

  Fly   483 LAFNLGYWLFYI 494
            ..||:.|||:|:
Zfish   507 SFFNIVYWLYYV 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	235/529 (44%)
		Neur_chan_LBD	47..256	CDD:280998	115/213 (54%)
		Neur_chan_memb	263..490	CDD:280999	105/274 (38%)
gabrb2a	NP_001019558.2	LIC	7..517	CDD:273305	235/529 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	251	1.000	Domainoid score	I2057
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	433	1.000	Inparanoid score	I1673
OMA	1	1.010	-	-		QHG47165
OrthoDB	1	1.010	-	-		D226476at33208
OrthoFinder	1	1.000	-	-		FOG0001081
OrthoInspector	1	1.000	-	-		otm25145
orthoMCL	1	0.900	-	-		OOG6_101786
Panther	1	1.100	-	-	LDO	PTHR18945
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2537
SonicParanoid	1	1.000	-	-		X650
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870