Protein Alignment Lcch3 and nAChRbeta3

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_525098.1
• Gene: nAChRbeta3 / 33228
• FlyBaseID: FBgn0031261
• Length: 441
• Species: Drosophila melanogaster
• Alignment Length: 408
• Identity: 78/408 - (19%)
• Similarity: 155/408 - (37%)
• Gaps: 60/408 - (14%)

  Fly    45 SNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYF 109
            :.:...||..::|.|.|.|.:|.:::.:...| |.|:|...|...:||..||||...:.. .||
  Fly    56 AGLFTNYDSDVQPVFQGTPTNVSLEMVVTYID-IDELNGKLTTHCWLNLRWRDEERVWQP-SQY- 117

  Fly   110 DDENDDGISDVLTLSGDFAEKIWVPD-TFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTT 173
                 |.|:.:...|.:    :|.|. |.|..|:...:.:..     |.|..||...:......|
  Fly   118 -----DNITQITLKSSE----VWTPQITLFNGDEGGLMAETQ-----VTLSHDGHFRWMPPAVYT 168

  Fly   174 LACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGVEDAE---------LPQFTIIGY 229
            ..|.:::..:|.|.|:|.::|.|:|..|        ..|..|....|         .|::.|:
  Fly   169 AYCELNMLNWPHDKQSCKLKIGSWGLKV--------VLPENGTARGESLDHDDLVQSPEWEIV-- 223

  Fly   230 ETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGIT 294
              :.|...::...|..:..:...||....:....|.|:..||:|:..:||:.......::.:...
  Fly   224 --DSRAHFVSQDYYGYMEYTLTAQRRSSMYTAVIYTPASCIVILALSAFWLPPHMGGEKIMINGL 286

  Fly   295 TVLTMTTISTGVRSSLPRIS-YVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKE 358
            .::.:..........||.:| ....:.|:.....:::..:.:....|.|...||..::..:.:::
  Fly   287 LIIVIAAFLMYFAQLLPVLSNNTPLVVIFYSTSLLYLSVSTIVEVLVLYLATGKHKRRLPEALRK 351

  Fly   359 CCPGKI------------GKSERSETCSTTEDIIELQD--------VRMSPIPSLRRGTYNATLD 403
            ...|.:            |:|:..:|....|...|..|        :..:.:|..:...::..|.
  Fly   352 LLHGHLGTWLLLSVFSTTGESQAEKTKEMDEHPYEEADEQESSPLGINHTEVPGAKANQFDWALL 416

  Fly   404 SIGTETMNLGKFPPSFRI 421
            :...:.::...|..:|.|
  Fly   417 ATAVDRISFVSFSLAFLI 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	78/408 (19%)
		Neur_chan_LBD	47..256	CDD:280998	51/218 (23%)
		Neur_chan_memb	263..490	CDD:280999	27/180 (15%)
nAChRbeta3	NP_525098.1	LIC	39..437	CDD:273305	78/408 (19%)
		Neur_chan_LBD	52..247	CDD:280998	50/219 (23%)
		Neur_chan_memb	255..434	CDD:280999	26/178 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447342
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940