Protein Alignment Lcch3 and Gabra6

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_068613.1
• Gene: Gabra6 / 29708
• RGDID: 61861
• Length: 453
• Species: Rattus norvegicus
• Alignment Length: 465
• Identity: 167/465 - (35%)
• Similarity: 251/465 - (53%)
• Gaps: 61/465 - (13%)

  Fly    38 ENVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAF 102
            |||::.:.|:|:|||.||||.|||....|..|:.:.||..:|:|.|:||:.::..|.|.||||.|
  Rat    30 ENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKF 94

  Fly   103 NIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYG 167
            .            |.:::|:|:.....|||.|||||.|.|.|..|::|..|||.||..:|.:.|.
  Rat    95 K------------GPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMHNGTILYT 147

  Fly   168 MRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGV----EDAELPQFTIIG 228
            ||.|....|.|.|..:|:|...|.::..||.|..|:::..||..|:..|    |.:.|.|:.:||
  Rat   148 MRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212

  Fly   229 YETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGI 293
            ...:....:..||.|..:::.|.|||.:|||:.|.|.|.|:.|:||.||||||.|:..||...||
  Rat   213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGI 277

  Fly   294 TTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKE 358
            ||||||||:|...|.|||::||..|:|.::.:||.|||:||:|:||||| :...:::|..::.:.
  Rat   278 TTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNY-FTNLQSQKAERQAQT 341

  Fly   359 CCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMN--LGKFP--PSF 419
            .....:.||:.:|  |...:|:...|.:.    .|::...:.||..:.:...:  |.:.|  ||.
  Rat   342 AAKPPVAKSKTTE--SLEAEIVVHSDSKY----HLKKRISSLTLPIVPSSEASKVLSRTPILPST 400

  Fly   420 RITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLA 484
            .:|                     |.:|             :|.|...:.||:|||::||::|..
  Rat   401 PVT---------------------PPLL-------------LPAIGGTSKIDQYSRILFPVAFAG 431

  Fly   485 FNLGYWLFYI 494
            |||.||:.|:
  Rat   432 FNLVYWIVYL 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	166/462 (36%)
		Neur_chan_LBD	47..256	CDD:280998	79/212 (37%)
		Neur_chan_memb	263..490	CDD:280999	77/230 (33%)
Gabra6	NP_068613.1	Neur_chan_LBD	33..240	CDD:280998	80/218 (37%)
		LIC	34..440	CDD:273305	163/458 (36%)
		Neur_chan_memb	247..437	CDD:280999	77/230 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810