Protein Alignment Lcch3 and lgc-57

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_496306.2
• Gene: lgc-57 / 191636
• WormBaseID: WBGene00001586
• Length: 473
• Species: Caenorhabditis elegans
• Alignment Length: 486
• Identity: 145/486 - (29%)
• Similarity: 233/486 - (47%)
• Gaps: 81/486 - (16%)

  Fly    38 ENVTQ--------TISNILQ---GYDIRLRPNFGGEPL-------HVGMDLTIASFDAISEVNMD 84
            |||||        .::.||:   .|      |....||       ||.:.:.|....:....:||
 Worm    28 ENVTQIEEDFKIDDVTRILKRVGNY------NRNAYPLLDQDLATHVDIQMYIEGMSSFHAQSMD 86

  Fly    85 YTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDV 149
            :.:.:|..:.|.|.||..|            ....:|.........:|.||.:|||.:.:..|||
 Worm    87 FQVDIYFQEKWVDHRLQHN------------NTKRILVKDPKLFGLLWHPDLYFANARTASFHDV 139

  Fly   150 TERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYW---KPT 211
            |:.|.||.:..:|.|.|..|.:.|:.||.||..||||||||.:.|.||.|....:::.|   .|.
 Worm   140 TQPNFLVWIYPNGTVWYDCRISLTVLCMQDLARYPLDSQNCGLRILSYAYDEEQLIIRWNGGNPV 204

  Fly   212 PV-RGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSW 275
            .| ||:   .:|...:...:...::::.|||::......|.:.|.|.:.:.|:|:|:.|||::||
 Worm   205 EVNRGI---RMPDMHLKHIKFYTKRDKYATGIWSSAVAEFHVDREITHHIIQSYIPTSLIVIISW 266

  Fly   276 VSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAV 340
            .|||::.||...||:|.|||:||:.|.|:..|.:||:.|.|||||:::..|..|||:|::|:..|
 Worm   267 FSFWLDVEAVPGRVSLSITTLLTLATQSSAARMALPQASDVKAIDVWMGTCMAFVFSAMIEFTVV 331

  Fly   341 NYTYWGKRAKKKIK-KVKECCPGKIGKSERSETCSTTE--DIIELQDVRMSPIPSLRRGTYNATL 402
            ||.     .::|:: |:|   |..:.:..........|  |.....:..:|...:|:....|||
 Worm   332 NYC-----VRRKVRTKIK---PRGLSEQVHDMVAQYREKKDKFNNGNCEISYEMALQPNEDNAT- 387

  Fly   403 DSIGTETMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKI--- 464
                              :.||:  ...::|...|..:..|..:|...||  ..|:..|.::
 Worm   388 ------------------VQRNF--EKKEVREMNQASLFVRRSLLPTSKR--KTIEDRINRVEEN 430

  Fly   465 -KDVNIIDKYSRMIFPISFLAFNLGYWLFYI 494
             |:...||:|||.:||::|:.||:.||::|:
 Worm   431 RKNAQKIDRYSRALFPLAFIIFNIFYWIYYL 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	144/483 (30%)
		Neur_chan_LBD	47..256	CDD:280998	63/222 (28%)
		Neur_chan_memb	263..490	CDD:280999	72/233 (31%)
lgc-57	NP_496306.2	Neur_chan_LBD	43..217	CDD:280998	58/194 (30%)
		LIC	44..460	CDD:273305	139/467 (30%)
		Neur_chan_memb	255..457	CDD:280999	72/232 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810