Protein Alignment Lcch3 and lgc-50

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_498637.3
• Gene: lgc-50 / 188633
• WormBaseID: WBGene00020605
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 143/522 - (27%)
• Similarity: 235/522 - (45%)
• Gaps: 86/522 - (16%)

  Fly    14 FFFLLGAQLQLIRCIRKDVLAGRLENVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAI 78
            |:|.........:|.|..:..|:|      |..:|..||..|.|.  .|.::|.::|.:.....|
 Worm    12 FYFSAATTNSPKKCSRNSINLGKL------IDTLLTDYDTHLLPE--AEGVNVTIELHVQGVSGI 68

  Fly    79 SEVNMDYTITMYLNQYWRDERLAF---NIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFAN 140
            ||:..|:::.:..::.|:|.||:|   |:            .:..:||..||.:|||.|||...|
 Worm    69 SEITGDFSLDVMYSEIWQDPRLSFKHLNV------------CATNITLKSDFRKKIWTPDTCIIN 121

  Fly   141 DKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVV 205
            .|:|.:|.....|..|.|..:|.|....|......|.::|..:|.||.:|.:.:|||.:...:|.
 Worm   122 SKSSSIHSSPSENTFVILYENGLVWSNFRLNVKTPCSVNLKMFPFDSLSCEIVLESYSFNTDEVR 186

  Fly   206 MYWKPTPVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILI 270
            :.|...|:..:|..|||.|.:||:.|:.::.....|::.|..:.|...|..|:::||:|.|:.|.
 Worm   187 LMWHDVPITMMEKVELPDFDLIGWSTDHQRLEYPNGIWDRAKVKFTFARRYGFYLFQSYFPTSLT 251

  Fly   271 VMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALL 335
            |:.|||.|:.:..:.|||:.||::::|.:|.....|...|||:||:|.:|::::...:|:|..|:
 Worm   252 VISSWVGFFFDVRSVSARITLGVSSLLALTFQFGNVLRHLPRVSYIKCLDVWMIFSVIFIFCTLV 316

  Fly   336 EYAAV-NYTYWG-----------------KRAKKKIKKVKECCPGKIGKSERSETCSTTEDIIEL 382
            |.|.| ....|.                 ::.:||..|..|...|.:|...|..
 Worm   317 ELAIVCQLNRWERERQIGSKVLGHWLNQIRKTRKKESKADEGGGGGVGGLLRKR----------- 370

  Fly   383 QDVRMSPIPSLRRGTYNATLDSIGTET-MNLGKFPPSFRITRNYGTGHSQL-------------R 433
                   ||.|.:....||..:.|..| |.....||:..:.....:.:|:|             .
 Worm   371 -------IPVLAQLKAAATDSNSGAATAMTTAIQPPNTNLNSITNSDNSKLVANNFTSIEHETYA 428

  Fly   434 RRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNI----IDKYSRMIFPISFLAFNLGYWLFYI 494
            ...:||.|      |..:|...||   .|..:|..|    :|:.|.::||:|||.||:.||..|.
 Worm   429 YEKKRGFS------HCFQRFVYAI---CPPDRDWTITSVQVDRCSMIMFPLSFLIFNVVYWSIYF 484

  Fly   495 LE 496
            ::
 Worm   485 MK 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	141/516 (27%)
		Neur_chan_LBD	47..256	CDD:280998	62/211 (29%)
		Neur_chan_memb	263..490	CDD:280999	68/262 (26%)
lgc-50	NP_498637.3	LIC	34..483	CDD:273305	137/495 (28%)
		Neur_chan_LBD	34..237	CDD:280998	64/222 (29%)
		Neur_chan_memb	245..480	CDD:280999	68/261 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810