Protein Alignment Lcch3 and lgc-41

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001360683.1
• Gene: lgc-41 / 183331
• WormBaseID: WBGene00008022
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 575
• Identity: 164/575 - (28%)
• Similarity: 245/575 - (42%)
• Gaps: 160/575 - (27%)

  Fly    40 VTQ-TISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFN 103
            :|| .|.|:||..:.|........||.|.:.:.:.|........|.:.:.:|:...|:|.|||.|
 Worm    26 LTQPNIYNLLQQSNTRPPTANASVPLGVKLGMYLESLGNFRSSEMSFDVDLYVYMSWQDPRLAHN 90

  Fly   104 IFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGM 168
             |..|           ||..:.:..::||:||.:|||.:.:...:||..|..:.:..||.|.|..
 Worm    91 -FSDY-----------VLINNDEIRKQIWLPDLYFANARQASFQEVTVPNFNLFVAPDGTVAYSC 143

  Fly   169 RFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYW-KPTPVRGVEDAELPQFTI------ 226
            |.|.|:||.::|.|||:|.|.|::.:.||.|....|.:.| ...|||..|:..||:|.|
 Worm   144 RCTLTVACSLNLRYYPMDQQLCSIRVLSYAYIAKQVNVTWFDKNPVRFNEEIGLPEFQIEHVSNA 208

  Fly   227 ------------IGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFW 279
                        ..|:::|         :..||.:..|.|:|||.:.|:|:|:.||||:||||||
 Worm   209 YCNGSYQYALTENSYKSDD---------FSCLSGNLFLSRSIGYNLVQSYIPTGLIVMISWVSFW 264

  Fly   280 INHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTY 344
            |:..|..|||.|..||::::||:..|:|..||::||.||||::...|..|||.||||:|.:| :|
 Worm   265 IDRRAVPARVTLSFTTLVSLTTLGNGLRFGLPQVSYAKAIDLWYGACMFFVFCALLEFATIN-SY 328

  Fly   345 WGKRAK-----KK--------------IKKVKEC------CPGKIGKSERSETCS-TTE------ 377
            ..|..|     ||              ::.:||.      ..|.:..:...:.|: :||
 Worm   329 MRKSEKFDSMAKKMQSVVLTGRTRDYLVRGIKESMRIAGGAAGNVVDALNDDWCTYSTENGRKSF 393

  Fly   378 -----DIIELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYG---TGHSQLRR 434
                 ||.|.....:||    ||..|.    .:.||     |.|      |.||   |....|..
 Worm   394 SAMVGDIFERAGNAISP----RRNRYR----GLKTE-----KSP------RGYGKPDTVQDILSE 439

  Fly   435 R-----------------------------------------AQRGISTRP-------------R 445
            |                                         .:...||:|             :
 Worm   440 RIKFIDNEFDFDTKEDDEIPGNMAMSIYDNVSCRKDEADSSSEETKFSTKPKRNGTNGTRKYIDK 504

  Fly   446 MLHALKRGASAIKATIPKI-----KDVNIIDKYSRMIFPISFLAFNLGYWLFYIL 495
            .|:...:..|.|.||..:|     :....|||..|.:||.:||.:|:.||.:|::
 Worm   505 SLNQSGQNDSLIVATYFQISANHSRHALKIDKSCRYLFPAAFLLWNVFYWWYYLV 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	163/571 (29%)
		Neur_chan_LBD	47..256	CDD:280998	64/227 (28%)
		Neur_chan_memb	263..490	CDD:280999	89/325 (27%)
lgc-41	NP_001360683.1	LIC	41..>332	CDD:273305	109/312 (35%)
		LGIC_TM	<527..557	CDD:365787	11/29 (38%)
		TM4 helix	530..554	CDD:349850	9/23 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910