Protein Alignment Lcch3 and lgc-55

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_507870.2
• Gene: lgc-55 / 180312
• WormBaseID: WBGene00013746
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 526
• Identity: 132/526 - (25%)
• Similarity: 231/526 - (43%)
• Gaps: 76/526 - (14%)

  Fly     4 FTRV-GVSCGLFFFLLGAQLQLIRCIRKD----VLAGRLENVTQTISNILQGYDIRLRPNFGGEP 63
            |.|: ..||.:...|....|.|.:...:|    ||....:..|:.::.:|..||..|.|...|
 Worm    47 FARISNGSCAMVSDLARGGLGLSQDSEEDEPFCVLGQAEKAATRILTELLSKYDRNLVPKMKG-- 109

  Fly    64 LHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDV--LTLSGD 126
            :.|.::|.|.....|||:....|:.:..:|.|.|..|:|         |:::|...:  |:||..
 Worm   110 VDVDVELLIQRVSEISEIQSSSTMHILFSQIWHDPGLSF---------EHEEGAHCLTNLSLSHR 165

  Fly   127 FAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCT 191
            ..:.||:|:....|.|.|.:|.....|..:.:..:|.|....|......|.||..::|:|...||
 Worm   166 MVDNIWLPNVCIVNSKGSAIHKSPTPNIFLAIFPNGTVWMNYRVVVESPCEMDFSFFPMDRVMCT 230

  Fly   192 VEIESYGYTVSDVVMYWK--PTPVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQR 254
            ...|||.:.|..|.::||  ..||..::|.:||.|.:..:...........||:.:|::....:|
 Worm   231 TIFESYAFNVGKVRLHWKRQGQPVEFIDDVKLPDFHMTKFVHEKATFIYPAGVWDQLNIKLLFRR 295

  Fly   255 NIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAI 319
            :.|:::.|.|||:..:|::||:|||::..:..|||.||:::::.:|...:.|..|||::||||.:
 Worm   296 SYGFYILQIYLPTYCMVLISWISFWLDRRSLPARVTLGVSSLMALTLQYSNVSRSLPKVSYVKGL 360

  Fly   320 DIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKK----------IKK--------VKECCPGKIGK 366
            |:::..|.|::|.:::|.|.|......|:.:..          |||        .|....|...:
 Worm   361 DLFMFGCIVYIFLSIVELAVVGSLEQRKQQRTNADGDFLSDDDIKKNIFQRTFSTKSFKSGYGAR 425

  Fly   367 SERSETCSTTEDIIELQDVRMS---------PIPSLRRGTYNATLDSIGTETMNLGKFPPSFRIT 422
            ..:...|::.||..|....|..         |.|.......:..:::.....|.:        :.
 Worm   426 HHQFSECASPEDGGEWPKTRTEWAERTYVECPEPEPPESNRHPEVENDSNNKMLV--------LV 482

  Fly   423 RNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNL 487
            |         :|||.|            ||....:...:.:......:|::.:.:|||:|...||
 Worm   483 R---------QRRASR------------KRRKRLMSGKLFQRWTAEDMDRFCQKLFPITFTFCNL 526

  Fly   488 GYWLFY 493
            .||::|
 Worm   527 IYWMYY 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	127/512 (25%)
		Neur_chan_LBD	47..256	CDD:280998	58/212 (27%)
		Neur_chan_memb	263..490	CDD:280999	58/253 (23%)
lgc-55	NP_507870.2	Neur_chan_LBD	88..295	CDD:280998	58/217 (27%)
		LIC	90..532	CDD:273305	120/481 (25%)
		Neur_chan_memb	304..>391	CDD:280999	31/86 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810