Protein Alignment Lcch3 and lgc-37

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_499662.2
• Gene: lgc-37 / 176694
• WormBaseID: WBGene00013914
• Length: 483
• Species: Caenorhabditis elegans
• Alignment Length: 509
• Identity: 155/509 - (30%)
• Similarity: 245/509 - (48%)
• Gaps: 91/509 - (17%)

  Fly    19 GAQLQLIRCIRKDVLAGR--------LENVTQTISNILQGYDIRLRP-NFGGEPLHVGMDLTIAS 74
            |...|.:..:::..|:.|        :...|:.:..||...|...|| |....||.|.:|::|.|
 Worm    15 GHHSQAVIDMKRQRLSSRSTTYNQTLIRYTTKVLDTILLNQDKNFRPVNPDNSPLQVEVDISIRS 79

  Fly    75 FDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFA 139
            ...:||.||::::..|..|.|.|.||||........:         :.|:....:.||:|||:..
 Worm    80 MGPVSEQNMEFSLDCYFRQKWLDRRLAFTPINPSKPE---------IPLASKMLKDIWIPDTYIR 135

  Fly   140 NDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDV 204
            |.:.|:||.:|..|.|.|:..||.|....|.|....|.|.|..:|:|:|.|.:|:.|.||...||
 Worm   136 NGRKSYLHTLTVPNILFRVRSDGQVHVSQRLTIRSRCQMFLKKFPMDTQACPIEVGSLGYFSKDV 200

  Fly   205 VMYWKPTPVRGVEDAELPQFTIIGYETNDRKE---RLATGVYQRLSLSFKLQRNIGYFVFQTYLP 266
            |..||...:.......|.|:.::....::|..   |.:......|::.|||||..||::.|.|.|
 Worm   201 VYKWKDVELDAKMGNTLSQYQVLSLSKSERNVSDFRFSDRNISVLNVYFKLQRQQGYYILQIYTP 265

  Fly   267 SILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVF 331
            ..|:|::||||||||.||:.|||:|||.|||:|:||..|:|:.||::|:..|:|:|::.||||:|
 Worm   266 CTLVVVMSWVSFWINKEASPARVSLGIMTVLSMSTIGFGLRTDLPKVSHSTALDVYILTCFVFLF 330

  Fly   332 AALLEYAAVNY---TYWGKRAKKKIKKVKEC----------CPGKIGKSERSETCSTTEDIIELQ 383
            ||::|||.:||   .|    .:|:|..:|..          ..|.:| :.|.:|....:..:|.:
 Worm   331 AAMVEYAVINYAQIVY----IRKQIHDLKGLEQNTAMGQMFTAGLMG-ARRRDTIQVDDLTVEKE 390

  Fly   384 DVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLH 448
            :.|:..:|..::..:.   |..|..:|       .:|:
 Worm   391 EARLKAVPWWKKLCFK---DEQGNTSM-------FYRM--------------------------- 418

  Fly   449 ALKRGASAIKATIPK--------IKDVNIIDKYSRMIFPISFLAFNLGYWLFYI 494
                   |:||.|.|        .:.||.||.:|::.||..::.||:.||:.|:
 Worm   419 -------AVKAAIAKKTLRNGDPAEVVNKIDNFSKLAFPTLYIIFNVFYWVAYL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	154/506 (30%)
		Neur_chan_LBD	47..256	CDD:280998	69/212 (33%)
		Neur_chan_memb	263..490	CDD:280999	75/247 (30%)
lgc-37	NP_499662.2	LIC	44..464	CDD:273305	150/477 (31%)
		Neur_chan_LBD	45..254	CDD:280998	69/217 (32%)
		Neur_chan_memb	262..461	CDD:280999	75/247 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810