Protein Alignment Lcch3 and Glrb

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_036018791.1
• Gene: Glrb / 14658
• MGIID: 95751
• Length: 530
• Species: Mus musculus
• Alignment Length: 524
• Identity: 176/524 - (33%)
• Similarity: 269/524 - (51%)
• Gaps: 80/524 - (15%)

  Fly    17 LLGAQLQLIRCIRK-DVLAGRLENVTQTISN-ILQGYDIRLRPNFGGEPLHVGMDLTIASFDAIS 79
            |||.|.....|.:. :.||....|.|..|.| :|..||.|:||||.|.|:.|.:::.|.||.:|.
Mouse    41 LLGLQACHHSCQQSPEDLARVPPNSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQ 105

  Fly    80 EVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNS 144
            |..|||.:.::|.|.|.|.||..         .:|...||.||:.....:.:|.||.||||:|::
Mouse   106 ETTMDYRVNIFLRQKWNDPRLKL---------PSDFRGSDALTVDPTMYKCLWKPDLFFANEKSA 161

  Fly   145 FLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWK 209
            ..||||:.|.|:.:..||.|...||.:.||:|.:||..:|:|:|.|.:::||:|||..|:...|:
Mouse   162 NFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQ 226

  Fly   210 P-TPVRGVEDAELPQFTI----IGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSIL 269
            . .||: :|...||||.|    |.| .|..|....||.|..:.:.|.|:|.:|:::...|.|::|
Mouse   227 SGDPVQ-LEKIALPQFDIKKEDIEY-GNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLL 289

  Fly   270 IVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAAL 334
            ||:|||:|||||.:|::|||.|||.:||::.:..|.:.:.||::|||||:|::|:.|.:|.||:|
Mouse   290 IVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASL 354

  Fly   335 LEYAAV----NYTYWGKRAKKKIKKVKECCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRR 395
            :|||.|    |.....:..|.:|.|.:: ..||.|.:.:..|.:.|...:.:..::..|: ..::
Mouse   355 VEYAVVQVMLNNPKRVEAEKARIAKAEQ-ADGKGGNAAKKNTVNGTGTPVHISTLQELPM-VCQQ 417

  Fly   396 GTYNATLDSIGTETMN-------------------------LGKFPPSFRITR----------NY 425
            .||.  ||...|:|:.                         :|..|..|.::.          |.
Mouse   418 ITYQ--LDGWPTDTLTTQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNN 480

  Fly   426 GTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYW 490
            |.|..|.:.:  :....:|.:..|.||                 ||.|:|.:||..||.||:.||
Mouse   481 GLGKPQAKNK--KPPPAKPVIPTAAKR-----------------IDLYARALFPFCFLFFNVIYW 526

  Fly   491 LFYI 494
            ..|:
Mouse   527 SIYL 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	175/521 (34%)
		Neur_chan_LBD	47..256	CDD:280998	83/213 (39%)
		Neur_chan_memb	263..490	CDD:280999	78/265 (29%)
Glrb	XP_036018791.1	LIC	64..529	CDD:273305	168/498 (34%)
		LGIC_ECD_GlyR_beta	89..275	CDD:349811	73/196 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810