Protein Alignment Lcch3 and Glra4

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_034427.2
• Gene: Glra4 / 14657
• MGIID: 95750
• Length: 456
• Species: Mus musculus
• Alignment Length: 502
• Identity: 187/502 - (37%)
• Similarity: 272/502 - (54%)
• Gaps: 90/502 - (17%)

  Fly    13 LFFFLLGAQLQLIRCIRKDVLAGRLENVTQTISNIL-------QGYDIRLRPNFGGEPLHVGMDL 70
            |.:.|.|..|..:...::||.:|...:...:.|:.|       .|||.|:||||.|.|::|..::
Mouse    12 LLWTLPGKVLLSVALAKEDVKSGLKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNI 76

  Fly    71 TIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPD 135
            .|.||.:::|..|||.:.::|.|.|.|.|||:.   :|.||.        |.|.....:.||.||
Mouse    77 FINSFGSVTETTMDYRVNVFLRQQWNDPRLAYR---EYPDDS--------LDLDPSMLDSIWKPD 130

  Fly   136 TFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYT 200
            .||||:|.:..|:||..|||:|:..:|.|.|.:|.|..|:|.|||..:|:|.|.||:::||:|||
Mouse   131 LFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYT 195

  Fly   201 VSDVVMYW-KPTP-VRGVEDAELPQFTI-----IGYETNDRKERLATGVYQRLSLSFKLQRNIGY 258
            ::|::..| :..| |:..|...||||.:     :||.|    :...||.:..:.:.|.|:|.:||
Mouse   196 MNDLMFEWLEDAPAVQVAEGLTLPQFILRDEKDLGYCT----KHYNTGKFTCIEVKFHLERQMGY 256

  Fly   259 FVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYL 323
            ::.|.|:||:|||:|||||||||.:|..|||.|||||||||||.|:|.|:|||::||||||||::
Mouse   257 YLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWM 321

  Fly   324 VMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKECCPGKIGKSERSETCSTTEDIIELQDVRMS 388
            .:|.:|||||||||||||:.   .|..|:..:::     :..:.:|.|     ||||
Mouse   322 AVCLLFVFAALLEYAAVNFV---SRQHKEFMRLR-----RRQRRQRME-----EDII-------- 365

  Fly   389 PIPSLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLHA---- 449
                 |...:                      ..|.||.||.   .:|:.|.......:::
Mouse   366 -----RESRF----------------------YFRGYGLGHC---LQARDGGPMEGSSIYSPQPP 400

  Fly   450 ---LKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYWLFY 493
               ||.|.:..|..:.:.|.   ||..||.:||.:||.||:.||:.|
Mouse   401 TPLLKEGETMRKLYVDRAKR---IDTISRAVFPFTFLVFNIFYWVVY 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	185/498 (37%)
		Neur_chan_LBD	47..256	CDD:280998	84/222 (38%)
		Neur_chan_memb	263..490	CDD:280999	89/233 (38%)
Glra4	NP_034427.2	LIC	9..444	CDD:273305	186/500 (37%)
		Strychnine-binding. /evidence=ECO:0000250|UniProtKB:O93430	236..241		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810