Protein Alignment Lcch3 and Gabra2

DIOPT Version :9

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_032092.1
• Gene: Gabra2 / 14395
• MGIID: 95614
• Length: 451
• Species: Mus musculus
• Alignment Length: 477
• Identity: 159/477 - (33%)
• Similarity: 235/477 - (49%)
• Gaps: 75/477 - (15%)

  Fly    28 IRKDVLAGRLENVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLN 92
            |::|.....:...|:.:..:|.|||.||||..|.....|..::.:.||..:|:.:|:|||.::..
Mouse    30 IQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFR 94

  Fly    93 QYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVR 157
            |.|:||||.|.            |..::|.|:...|.|||.|||||.|.|.|..|::|..|||:|
Mouse    95 QKWKDERLKFK------------GPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLR 147

  Fly   158 LGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGVEDA--- 219
            :..||.:.|.||.|....|.|.|..:|:|:.:|.::..||.||.|:|...|.......|:.|
Mouse   148 IQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDG 212

  Fly   220 -ELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHE 283
             .|.|:.::|........:.:||.|..::..|.|:|.|||||.|||||.|:.|:||.||||:|.|
Mouse   213 SRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 277

  Fly   284 ATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNY------ 342
            :..||...|:||||||||:|...|:|||:::|..|:|.::.:|:.|||:||:|:|.|||
Mouse   278 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGW 342

  Fly   343 TYWGKRAKKKIKKVKECCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGT 407
            .:.||......||.|                    ..:.:|:              ||...::..
Mouse   343 AWDGKSVVNDKKKEK--------------------GSVMIQN--------------NAYAVAVAN 373

  Fly   408 ETMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDK 472
            ...||.|.|....|:::                :|.|......:...:..|.|   ...|:.||:
Mouse   374 YAPNLSKDPVLSTISKS----------------ATTPEPNKKPENKPAEAKKT---FNSVSKIDR 419

  Fly   473 YSRMIFPISFLAFNLGYWLFYI 494
            .||::||:.|..|||.||..|:
Mouse   420 MSRIVFPVLFGTFNLVYWATYL 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	158/474 (33%)
		Neur_chan_LBD	47..256	CDD:280998	75/212 (35%)
		Neur_chan_memb	263..490	CDD:280999	72/232 (31%)
Gabra2	NP_032092.1	LIC	25..440	CDD:273305	158/474 (33%)
		LGIC_ECD_GABAAR_A2	47..249	CDD:349836	74/213 (35%)
		Cys-loop	166..180	CDD:349836	5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..408		2/34 (6%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910